Cardiovascular diseases (CVDs) are known as the major cause of death worldwide. In spite
of tremendous advancements in medical therapy, the gold standard for CVD treatment is still …

The advances in biotechnology, biomechanics, and biomaterials can be used to develop
organ models that aim to accurately emulate their natural counterparts. Heart disease, one …

The application of cyclic strain is known to enhance myoblast differentiation and muscle
growth in vitro and in vivo. However, current techniques apply strain to full tissues or cell …

In the past two decades, relevant advances have been made in the generation of
engineered cardiac constructs to be used as functional in vitro models for cardiac research …

Physical stimuli are crucial for the structural and functional maturation of tissues both in vivo
and in vitro. In tissue engineering applications, bioreactors have become fundamental and …

Myocardial infarctions are one of the most common forms of cardiac injury and death
worldwide. Infarctions cause immediate necrosis in a localized region of the myocardium …

Since cardiovascular diseases (CVDs) are globally one of the leading causes of death, of
which myocardial infarction (MI) can cause irreversible damage and decrease survivors' …

Highlights•Replacement tissues are being created using tissue engineering techniques.•
Engineered 3D tissue platforms can be used for drug screening and device testing.•High …

Cardiovascular diseases (CVD) are the leading cause of death around the world, being
responsible for 31.8% of all deaths in 2017 (Roth, GA et al. The Lancet 2018, 392, 1736 …

Heart failure remains the leading cause of death worldwide, creating a pressing need for
better preclinical models of the human heart. Tissue engineering is crucial for basic science …