Elephant genomes reveal accelerated evolution in mechanisms underlying disease defenses

M Tollis, E Ferris, MS Campbell… - Molecular Biology …, 2021 - academic.oup.com
Disease susceptibility and resistance are important factors for the conservation of
endangered species, including elephants. We analyzed pathology data from 26 zoos and …

Epigenetic clock and methylation studies in elephants

NA Prado, JL Brown, JA Zoller, A Haghani, M Yao… - Aging cell, 2021 - Wiley Online Library
Age‐associated DNA‐methylation profiles have been used successfully to develop highly
accurate biomarkers of age (" epigenetic clocks") in humans, mice, dogs, and other species …

Epigenetic clock and methylation study of oocytes from a bovine model of reproductive aging

P Kordowitzki, A Haghani, JA Zoller, CZ Li, K Raj… - Aging cell, 2021 - Wiley Online Library
Cattle are an attractive animal model of fertility in women due to their high degree of
similarity relative to follicle selection, embryo cleavage, blastocyst formation, and gestation …

Universal annotation of the human genome through integration of over a thousand epigenomic datasets

H Vu, J Ernst - Genome biology, 2022 - Springer
Background Genome-wide maps of chromatin marks such as histone modifications and
open chromatin sites provide valuable information for annotating the non-coding genome …

[HTML][HTML] Multi-tissue methylation clocks for age and sex estimation in the common bottlenose dolphin

TR Robeck, Z Fei, A Haghani, JA Zoller… - Frontiers in Marine …, 2021 - frontiersin.org
Accurate identification of individual ages within wild bottlenose dolphins (Tursiops truncatus)
is critical for determining population health and the development of population management …