Antiproteinases such as alpha‐2‐macroglobulin (A2M) play a role in hemostasis. A2M is
highly conserved throughout evolution and is a high molecular weight homo‐tetrameric …

Background: Wound healing is a complicated biological process that leads to the
regeneration of damaged skin tissue. Determining the methods to promote wound healing …

Various vaccines were developed to reduce the spread of the Severe Acute Respiratory
Syndrome Cov-2 (SARS-CoV-2) virus. Quickly after the start of vaccination, reports emerged …

Dear Editor, With great interest, we read the publication by Sinegre et al.[1] describing the
role of prothrombin conversion (PC) and thrombin decay in cirrhosis patients. The authors …

Thrombosis is a major clinical complication of COVID-19 infection. COVID-19 patients show
changes in coagulation factors that indicate an important role for the coagulation system in …

Background Patients with ischemic stroke at a young age (18-50 years) have an increased
long-term risk of recurrent ischemic events. Hypercoagulability may contribute to this high …

Abstract Introduction Hutchinson-Gilford Progeria Syndrome (HGPS) is an ultra-rare
premature aging genetic disorder caused by a point mutation in the lamin A gene, LMNA …

Factor (F) VIII deficiency causes bleeding in haemophilia A patients because of the reduced
formation of procoagulant enzyme thrombin, which is needed to make the blood clot. We …

There is ongoing debate as to whether abacavir (ABC) increases the risk for cardiovascular
disease (CVD) in people living with HIV (PLHIV) and the mechanisms underlying this …

Background Thrombin generation (TG) in the presence of thrombomodulin (TG-TM) in the
plasma of patients with cirrhosis (PWC) is tilted toward a hypercoagulable phenotype. Low …