Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …
Hesperidin and SARS-CoV-2: New light on the healthy function of citrus fruits
P Bellavite, A Donzelli - Antioxidants, 2020 - mdpi.com
Among the many approaches to Coronavirus disease 2019 (COVID-19) prevention, the
possible role of nutrition has so far been rather underestimated. Foods are very rich in …
possible role of nutrition has so far been rather underestimated. Foods are very rich in …
Risk factors associated with clinical outcomes in 323 coronavirus disease 2019 (COVID-19) hospitalized patients in Wuhan, China
Background With evidence of sustained transmission in more than 190 countries,
coronavirus disease 2019 (COVID-19) has been declared a global pandemic. Data are …
coronavirus disease 2019 (COVID-19) has been declared a global pandemic. Data are …
Role of the ACE2/angiotensin 1–7 axis of the renin–angiotensin system in heart failure
Heart failure (HF) remains the most common cause of death and disability, and a major
economic burden, in industrialized nations. Physiological, pharmacological, and clinical …
economic burden, in industrialized nations. Physiological, pharmacological, and clinical …
COVID‐19 and diabetes: is there enough evidence?
M Tadic, C Cuspidi, C Sala - The Journal of Clinical …, 2020 - Wiley Online Library
The pandemic of COVID‐19, a disease caused by a novel coronavirus SARS‐CoV‐2, is
associated with significant morbidity and mortality. Recent data showed that hypertension …
associated with significant morbidity and mortality. Recent data showed that hypertension …
Diabetes and metabolic syndrome as risk factors for COVID-19
M Marhl, V Grubelnik, M Magdič, R Markovič - Diabetes & Metabolic …, 2020 - Elsevier
Background and aims Clinical evidence exists that patients with diabetes are at higher risk
for Coronavirus disease 2019 (COVID-19). We investigated the physiological origins of this …
for Coronavirus disease 2019 (COVID-19). We investigated the physiological origins of this …
ACE2 deficiency worsens epicardial adipose tissue inflammation and cardiac dysfunction in response to diet-induced obesity
Obesity is increasing in prevalence and is strongly associated with metabolic and
cardiovascular disorders. The renin-angiotensin system (RAS) has emerged as a key …
cardiovascular disorders. The renin-angiotensin system (RAS) has emerged as a key …
Rutin: A Potential Antiviral for Repurposing as a SARS-CoV-2 Main Protease (Mpro) Inhibitor
PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Various computational studies, including in silico ones, have identified several existing
compounds that could serve as effective inhibitors of the SARS-CoV-2 main protease …
compounds that could serve as effective inhibitors of the SARS-CoV-2 main protease …
Mechanisms of COVID-19 pathogenesis in diabetes
C Aluganti Narasimhulu… - American Journal of …, 2022 - journals.physiology.org
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) virus, is a global pandemic impacting 254 million people in …
coronavirus 2 (SARS-CoV-2) virus, is a global pandemic impacting 254 million people in …
Type-2 diabetes as a risk factor for severe COVID-19 infection
The current outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), termed coronavirus disease 2019 (COVID-19), has generated a notable challenge …
CoV-2), termed coronavirus disease 2019 (COVID-19), has generated a notable challenge …