[HTML][HTML] Bisphosphonate conjugation for bone specific drug targeting

KB Farrell, A Karpeisky, DH Thamm, S Zinnen - Bone reports, 2018 - Elsevier
Bones provide essential functions and are sites of unique biochemistry and specialized
cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has …

Advanced technologies for oral controlled release: cyclodextrins for oral controlled release

PJ Salústio, P Pontes, C Conduto, I Sanches… - Aaps Pharmscitech, 2011 - Springer
Cyclodextrins (CDs) are used in oral pharmaceutical formulations, by means of inclusion
complexes formation, with the following advantages for the drugs:(1) solubility, dissolution …

Unveiling the intricate supramolecular chemistry of γ-cyclodextrin-epigallocatechin gallate inclusion complexes

P Kumar, VK Bhardwaj, R Purohit - Industrial & Engineering …, 2024 - ACS Publications
Green tea's main polyphenol, epigallocatechin-gallate (EgCg), garners attention for diverse
health-promoting properties. Due to the limited bioavailability of EgCg, drug formulation …

An oral polyphenol host-guest nanoparticle for targeted therapy of inflammatory bowel disease

C Zhang, F Zeng, Z Fan, Z He, L Tai, Q Peng, Y Zhang… - Acta Biomaterialia, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a global public health challenge that affects millions of
people. Current medical treatments for IBD are not fully effective and may cause undesirable …

PEGylated reduced graphene oxide as nanoplatform for targeted gene and drug delivery

E Demirel, YY Durmaz - European Polymer Journal, 2023 - Elsevier
Combination therapies involving anticancer drugs and gene therapy agents have become a
potential treatment for different cancer types reducing the side effects of anticancer drugs …

Cyclodextrins as multi-functional ingredients in dentistry

SS Braga - Pharmaceutics, 2023 - mdpi.com
Cyclodextrins are present in a variety of oral hygiene compositions. The present work
describes the role of cyclodextrins in several toothpastes and mouthwashes that are already …

Facile synthesis of β-cyclodextrin-dextran polymers by “click” chemistry

TT Nielsen, V Wintgens, C Amiel, R Wimmer… - …, 2010 - ACS Publications
Three series of novel water-soluble β-cyclodextrin-dextran polymers have been prepared by
“click” chemistry. The polymers were synthesized from alkyne-modified dextrans (AMDs) …

Dual labeling of biomolecules by using click chemistry: A sequential approach

P Kele, G Mezö, D Achatz… - Angewandte Chemie …, 2009 - epub.uni-regensburg.de
Click by click: Dual labeling of model compounds was carried out by using copper-free and
copper-mediated click chemistry in a sequential manner. This method was used to introduce …

Smart delivery of antitumoral platinum complexes from biomimetic hydroxyapatite nanocrystals

M Iafisco, B Palazzo, M Marchetti, N Margiotta… - Journal of Materials …, 2009 - pubs.rsc.org
This study widens the role of biomimetic hydroxyapatite (HA) nanocrystals as bone
substitutes and describes how they can be used as bone-specific drug delivery devices for …

Mucoadhesive poloxamer-based hydrogels for the release of HP-β-cd-complexed dexamethasone in the treatment of buccal diseases

R Diaz-Salmeron, B Toussaint, N Huang… - Pharmaceutics, 2021 - mdpi.com
Oral lichen planus (OLP) is an ongoing and chronic inflammatory disease affecting the
mucous membrane of the oral cavity. Currently, the treatment of choice consists in the direct …