Oxidative stress: The core pathogenesis and mechanism of Alzheimer's disease

R Bai, J Guo, XY Ye, Y Xie, T Xie - Ageing research reviews, 2022 - Elsevier
As the number of patients with Alzheimer's disease (AD) increases, it brings great suffering
to their families and causes a heavy socioeconomic burden to society. A vast amount of …

Role of oxidative damage in alzheimer's disease and neurodegeneration: From pathogenic mechanisms to biomarker discovery

FR Buccellato, M D'Anca, C Fenoglio, E Scarpini… - Antioxidants, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder accounting for over 50% of all
dementia patients and representing a leading cause of death worldwide for the global …

Deregulated mitochondrial microRNAs in Alzheimer's disease: focus on synapse and mitochondria

P Gowda, PH Reddy, S Kumar - Ageing research reviews, 2022 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia and is currently one of the
biggest public health concerns in the world. Mitochondrial dysfunction in neurons is one of …

Ginsenoside Rg1 in neurological diseases: From bench to bedside

S Yang, J Wang, P Cheng, L Chen, J Hu… - Acta Pharmacologica …, 2023 - nature.com
Ginseng has been used in China as a superior medicinal material for thousands of years
that can nourish the five internal organs, calm the mind and benefit wisdom. Due to its anti …

Roles of oxidative stress in synaptic dysfunction and neuronal cell death in Alzheimer's disease

G Plascencia-Villa, G Perry - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a brain disorder that progressively undermines memory and
thinking skills by affecting the hippocampus and entorhinal cortex. The main …

The neurobiology and therapeutic potential of multi-targeting β-secretase, glycogen synthase kinase 3β and acetylcholinesterase in Alzheimer's disease

MG Fronza, D Alves, D Praticò, L Savegnago - Ageing research reviews, 2023 - Elsevier
Alzheimer's Disease (AD) is the most common form of dementia, affecting almost 50 million
of people around the world, characterized by a complex and age-related progressive …

Mitochondrial impairments in aetiopathology of multifactorial diseases: common origin but individual outcomes in context of 3P medicine

L Koklesova, M Samec, A Liskova, K Zhai… - EPMA Journal, 2021 - Springer
Mitochondrial injury plays a key role in the aetiopathology of multifactorial diseases
exhibiting a “vicious circle” characteristic for pathomechanisms of the mitochondrial and …

Association of Oxidative Stress–Induced Nucleic Acid Damage with Psychiatric Disorders in Adults: A Systematic Review and Meta-Analysis

A Jorgensen, IB Baago, Z Rygner… - JAMA …, 2022 - jamanetwork.com
Importance Nucleic acid damage from oxidative stress (NA-OXS) may be a molecular
mechanism driving the severely increased morbidity and mortality from somatic causes in …

[HTML][HTML] Ambient particulate matter compositions and increased oxidative stress: Exposure-response analysis among high-level exposed population

W Hu, Y Wang, T Wang, Q Ji, Q Jia, T Meng, S Ma… - Environment …, 2021 - Elsevier
Background Oxidative stress has been suggested to be one of the key drivers of health
impact of particulate matter (PM). More studies on the oxidative potential of PM alone, but …

[HTML][HTML] Plant foods rich in antioxidants and human cognition: a systematic review

L Baroni, AR Sarni, C Zuliani - Antioxidants, 2021 - mdpi.com
Oxidative stress can compromise central nervous system integrity, thereby affecting
cognitive ability. Consumption of plant foods rich in antioxidants could thereby protect …