Exploiting the gut microbiome for brain tumour treatment

L Keane, JF Cryan, JP Gleeson - Trends in Molecular Medicine, 2024 - cell.com
Increasing evidence suggests that the gut microbiome plays a key role in a host of
pathological conditions, including cancer. Indeed, the bidirectional communication that …

Role of gut microbiota in regulating immune checkpoint inhibitor therapy for glioblastoma

H Zhang, Y Hong, T Wu, E Ben, S Li, L Hu… - Frontiers in …, 2024 - frontiersin.org
Glioblastoma (GBM) is a highly malignant, invasive, and poorly prognosed brain tumor.
Unfortunately, active comprehensive treatment does not significantly prolong patient …

The Role of Bacteria in Central Nervous System Tumors: Opportunities and Challenges

R Zhang, X Li, S Zhang - Microorganisms, 2024 - mdpi.com
Tumors of the central nervous system (CNS) are severe and refractory diseases with poor
prognosis, especially for patients with malignant glioblastoma and brain metastases …

Enhancing cancer immunotherapy and antiangiogenic therapy by regulating gut microbes: Opportunities and challenges

J Xu, Y Tian, D Hu, X Yan, L Yang - MedComm–Oncology, 2024 - Wiley Online Library
As the largest microecosystem in the human body, gut microbes (GMs) and their metabolites
play an important role in regulating human health. In recent years, immune checkpoint …

Effect of antibiotic drug use on outcome and therapy-related toxicity in patients with glioblastoma—A retrospective cohort study

L Götz, T Ansafi, M Gerken… - Neuro-Oncology …, 2024 - academic.oup.com
Background Glioblastoma (GB) is the most frequent malignant brain tumor and has a dismal
prognosis. In other cancers, antibiotic use has been associated with severity of …

Exploring the role of gut microbiota and ketogenic diet on glioma growth and tumor microenvironment

J Maqbool - 2025 - iris.uniroma1.it
Glioblastoma (GBM) is the most prevalent malignant brain tumor with few therapeutic
options. Recently, several studies have demonstrated a close association between gut …

The role of β-Hydroxy-β-methyl butyrate (HMB) in glioma growth suppression in mice

RK RIZWAN KHAN - 2025 - iris.uniroma1.it
Glioblastoma (GBM) represents one of the most aggressive malignancies of the central
nervous system (CNS), characterized by limited therapeutic options and high recurrence …

From the gut to the brain: effects of bowel inflammation on synaptic transmission and glial properties

G Scaringi - 2025 - iris.uniroma1.it
Inflammatory bowel diseases (IBD) affect the gastrointestinal tract and can lead to extra-
intestinal manifestations associated with cerebral function, including depression and …