A longstanding research goal has been to understand the nature and role of copper–oxygen
intermediates within copper-containing enzymes and abiological catalysts. Synthetic …

Copper is one of the most abundant and less toxic transition metals. Nature takes advantage
of the bioavailability and rich redox chemistry of Cu to carry out oxygenase and oxidase …

Particulate methane monooxygenase (pMMO) is an enzyme that oxidizes methane to
methanol with high activity and selectivity. Limited success has been achieved in …

Phenols are important starting materials, intermediates, and functional elements of a very
broad range of chemicals and materials. They are large-volume products of benzene …

Until recently, computational tools were mainly used to explain chemical reactions after
experimental results were obtained. With the rapid development of software and hardware …

The selective functionalization of strong C− H bonds and the oxidation of water by cheap
and nontoxic metals are some of the key targets of chemical research today. It has been …

Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial
respiratory electron transport chain, which utilize a unique heterobinuclear active site to …

Cu-exchanged small-pore zeolites (CHA and AEI) form methanol from methane (> 95%
selectivity) using a 3-step cyclic procedure (Wulfers et al. Chem. Commun. 2015, 51, 4447 …

Nature uses dioxygen as a key oxidant in the transformation of biomolecules. Among the
enzymes that are utilized for these reactions are copper-containing metalloenzymes, which …

A structural unit found in the active site of some copper proteins, the histidine brace, is
comprised of an N-terminal histidine that chelates a single copper ion through its amino …