Role of Histone Deacetylases in the Pathogenesis of Salivary Gland Tumors and Therapeutic Targeting Options

M Manou, DS Kanakoglou, T Loupis… - International Journal of …, 2023 - mdpi.com
Salivary gland tumors (SGTs) comprise a rare and heterogenous category of
benign/malignant neoplasms with progressively increasing knowledge of the molecular …

Diagnostic accuracy of pan‐TRK immunohistochemistry in differentiating secretory carcinoma from acinic cell carcinoma of salivary gland—A systematic review

P Sharma, N Sivakumar… - Journal of Oral Pathology & …, 2023 - Wiley Online Library
Background Secretory carcinoma (SC) is a well‐established salivary gland malignancy that
has earned its popularity for its unique clinicopathological behavior. Although it is an …

Mucoepidermoid carcinoma may be devoid of squamoid cells by immunohistochemistry: expanding the histologic and immunohistochemical spectrum of MAML2 …

JA Bishop, LDR Thompson, B Siegele, J Gagan… - …, 2023 - Wiley Online Library
Mucoepidermoid carcinoma (MEC) is historically defined by a mix of squamoid,
intermediate, and mucous cells, but we have recently encountered several cases lacking …

Salivary Gland Neoplasms With a Unique Trabecular Histology and MAML2 Translocation: A Trabecular Variant of a Mucoepidermoid Carcinoma

B Ahn, SH Choi, D Kim, D Kim… - The American Journal of …, 2023 - journals.lww.com
Mucoepidermoid carcinomas (MECs) are the most common salivary gland malignancy and
have a diverse histology. Many histologic variants of MEC have now been confirmed with …

Inhibition of HDAC and signal transduction pathways induces tight junctions and promotes differentiation in p63-positive salivary duct adenocarcinoma

M Nakano, K Ohwada, Y Shindo, T Konno, T Kohno… - Cancers, 2022 - mdpi.com
Simple Summary The p53 family p63 gene is essential for the proliferation and
differentiation of various epithelial cells, and it is overexpressed in some salivary gland …

Polymorphous Adenocarcinoma: A Systematic Review of the Literature and Presentation of Two Cases in a Less-Considered Anatomical Site

R Mauceri, M Coppini, G Alecci, A Cordova… - Cancers, 2024 - mdpi.com
Simple Summary Polymorphous adenocarcinoma (PAC), the second most prevalent
malignant tumour of the minor salivary glands, primarily affects the palate but can also …

Diagnostic utility of expression pattern of S100/mammaglobin/SOX10/DOG 1 immunohistochemistry in differentiation of secretory and acinic cell carcinoma: a …

G Sharma, M Kamboj, A Narwal, R Keerthika… - Indian Journal of …, 2024 - Springer
Secretory carcinoma (SC) is a relatively new disease entity, separate from acinic cell
carcinoma (AciCC), which frequently displays ETV6-NTRK3 gene fusion. However, the …

[HTML][HTML] Effects of bisphenol A on murine salivary glands and human tumor cell lines

GK da Silva, JAA de Arruda, TFA Almeida… - Experimental and …, 2023 - Elsevier
Bisphenol A (BPA) is an endocrine-disrupting chemical with a potential role in endocrine
cancers. However, the effects of BPA on the salivary glands have been barely explored. We …

Microsecretory adenocarcinoma of the hard palate: a case report and literature review

Y Lu, Y Wen, S Feng, W Huang - Diagnostic Pathology, 2024 - Springer
Microsecretory adenocarcinoma (MSA) is a new type of salivary gland neoplasm identified
in the 2022 World Health Organization Classification of Head and Neck Tumour (Skalova et …

The Challenge of “Monomorphic” Mucoepidermoid Carcinoma—Report of a Rare Case with Pure Spindle-Clear Cell Morphology

X Qu, EJC Chew, S Selvarajan, B Wu, A Agaimy… - Head and Neck …, 2023 - Springer
Background Mucoepidermoid carcinoma is a malignant salivary gland tumor which, in most
cases, is composed of variable proportions of mucous, epidermoid, and intermediate cells …