The fast technological development, particularly single nucleotide polymorphism array, array-
comparative genomic hybridization, and whole exome sequencing, has led to the discovery …

While most supernumerary teeth are idiopathic, they can be associated with a number of
Mendelian syndromes. However, this can also be a coincidental finding, since …

TRPS1 has been recently demonstrated as a highly sensitive and specific marker for breast
carcinomas. To further explore TRPS1's utility in breast carcinoma, we systematically …

Whole-body MRI (WBMRI) is an integral part of screening infants, children, and adolescents
for presymptomatic neoplasms in certain cancer predisposition syndromes, which include Li …

DNA copy number variants (CNVs) account for approximately 300 Mb of sequence variation
in the normal human genome. Significant numbers of pathogenic CNVs contribute toward …

The GATA-type zinc finger transcription factor TRPS1 has been implicated in breast cancer.
However, its precise role remains unclear, as both amplifications and inactivating mutations …

Perturbed epigenomic programs play key roles in tumorigenesis, and chromatin modulators
are candidate therapeutic targets in various human cancer types. To define singular and …

Liver metastasis remains the primary cause of mortality in patients with colon cancer.
Identifying specific driver gene mutations that contribute to metastasis may offer viable …

RAD21 encodes a key component of the cohesin complex, and variants in RAD21 have
been associated with Cornelia de Lange Syndrome (CdLS). Limited information on …

Non‐invasive prenatal screening (NIPS) has revolutionized the approach to prenatal fetal
aneuploidy screening. Many commercial providers now offer analyses for sub‐chromosomal …