Next generation sequencing is in the process of evolving from a technology used for
research purposes to one which is applied in clinical diagnostics. Recently introduced high …

B cell and T cell receptor repertoires compose the adaptive immune receptor repertoire
(AIRR) of an individual. The AIRR is a unique collection of antigen-specific receptors that …

We profiled adaptive immunity in COVID-19 patients with active infection or after recovery
and created a repository of currently> 14 million B and T cell receptor (BCR and TCR) …

Abstract Patients with Wiskott–Aldrich syndrome (WAS) lacking a human leukocyte antigen-
matched donor may benefit from gene therapy through the provision of gene-corrected …

Monitoring the T cell receptor (TCR) repertoire in health and disease can provide key
insights into adaptive immune responses, but the accuracy of current TCR sequencing …

One of the hallmarks of B lymphoid malignancies is a B cell clone characterized by a unique
footprint of clonal immunoglobulin (IG) gene rearrangements that serves as a diagnostic …

PURPOSE We compared 2 years of rituximab maintenance (RM) with a response-adapted
postinduction approach in patients with follicular lymphoma who responded to induction …

Classic Hodgkin lymphoma (cHL) is the cancer type most susceptible to antibodies targeting
programmed cell death protein 1 (PD1) and is characterized by scarce Hodgkin and Reed …

Lymphomas are heterogeneous tumors with striking genetic diversity and variable outcomes
even within pathologic diagnoses. Treatment response assessment relies on radiologic and …

Reliable and comprehensive monitoring data are required to trace and counteract
biodiversity loss. High-throughput metabarcoding using DNA extracted from community …