Metronomic chemotherapy and drug repurposing: A paradigm shift in oncology

N Jan, S Sofi, H Qayoom, A Shabir, BU Haq, MA Macha… - Heliyon, 2024 - cell.com
Cancer represents a significant global health and economic burden due to its high mortality
rates. While effective in some instances, traditional chemotherapy often falls short of entirely …

[HTML][HTML] Phyto-therapeutics as anti-cancer agents in breast cancer: Pathway targeting and mechanistic elucidation

A Almilaibary - Saudi Journal of Biological Sciences, 2024 - Elsevier
Cancer of the breast is the mainly prevalent class of cancer in females diagnosed over the
globe. It also happens to be the 2nd most prevalent reason of cancer-related deaths among …

[HTML][HTML] Mechanistic elucidation of Juglanthraquinone C targeting breast cancer: a network pharmacology-based investigation

H Qayoom, M Alkhanani, A Almilaibary… - Saudi Journal of …, 2023 - Elsevier
Breast cancer is the leading cause of death among women worldwide. Despite the recent
treatment options like surgery, chemotherapy etc. the lethality of breast cancer is alarming …

A network pharmacology-based investigation of brugine reveals its multi-target molecular mechanism against Breast Cancer

H Qayoom, M Alkhanani, A Almilaibary, SA Alsagaby… - Medical Oncology, 2023 - Springer
Breast cancer represents the leading cause of mortality among women worldwide. Since the
complexity of breast cancer as a disease resides in its heterogeneity as it consists of several …

[HTML][HTML] A comprehensive analysis of notch signaling genes in breast cancer: expression pattern and prognostic significance

S Sofi, H Qayoom, N Jan, N Khaliq… - Advances in cancer …, 2023 - Elsevier
The most recurrent type of cancer among women is breast cancer which is an intricate
disease with high intertumoral and intratumoral heterogeneity. Such variability is a key factor …

Proteomics: a groundbreaking development in cancer biology

MA Mir, H Qayoom, S Sofi, N Jan - Proteomics, 2023 - Elsevier
Proteins are the basic unit of any living organism. Proteins are comprised of a variety of
amino acids that drive the structure, stability, and function of proteins. Proteins are the …

[HTML][HTML] Decoding the molecular mechanism of stypoldione against breast cancer through network pharmacology and experimental validation

H Qayoom, B Alshehri, BU Haq, A Almilaibary… - Saudi Journal of …, 2023 - Elsevier
Breast cancer is the primary factor contributing to female mortality worldwide. The incidence
has overtaken lung cancer. It is the most difficult illness due to its heterogeneity and is made …

Introduction to breast cancer

MA Mir, H Qayoom - Therapeutic potential of cell cycle kinases in breast …, 2023 - Springer
Breast cancer is the leading cause of mortality among women worldwide. Being a
heterogenous disease it comprises many different subtypes that differ in their pathological …

[图书][B] Cytokine and Chemokine Networks in Cancer

MA Mir - 2023 - Springer
During the past 40 years, cytokines and chemokines have been extensively investigated as
either cancer targets or cancer treatments. A strong preclinical rationale supports therapeutic …

[HTML][HTML] Prognostic significance and expression pattern of glucose related genes in breast cancer: A comprehensive computational biology approach

B Alshehri - Saudi Journal of Biological Sciences, 2024 - Elsevier
Breast cancer (BC) is the most common type of malignancy globally and the main reason
why women die from tumours. The Warburg effect, a characteristic of tumor, describes how …