Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …

Background Gout is the most common form of inflammatory arthritis, affecting 41 million
adults worldwide. The global burden of gout has been increasing over the last three …

Abstract Purpose of Review In chronic kidney disease (CKD), plasma uric acid levels are
increased because of the decrease in glomerular filtration rate. However, in addition to CKD …

Aims Blood uric acid (UA) levels are frequently elevated in patients with heart failure and
reduced ejection fraction (HFrEF), may lead to gout and are associated with worse …

A direct relationship between serum uric acid levels and hypertension, cardiovascular, renal
and metabolic diseases has been reported in many basic and epidemiological studies …

While there is consensus on starting urate-lowering therapy (ULT) in cases of symptomatic
hyperuricemia, the frequent condition of asymptomatic hyperuricemia (AH) remains a …

Gout is the most prevalent form of inflammatory arthritis, with a strong impact on individual
health and healthcare systems. This article reviews clinical and experimental evidences …

The relationship between serum uric acid (SUA) and hypertension has been a subject of
increasing interest since the 1870 discovery by Frederick Akbar Mahomed. Several …

Aims To pool the effects of sodium‐glucose cotransporter‐2 (SGLT2) inhibitors on gout and
to investigate the association of these effects with baseline serum uric acid (SUA), SUA …

Uric acid (UA) is the end product of purine metabolism, and its concentration in blood can
increase in humans, great apes, and dalmatian dogs as a consequence of a genetic …