Targeting myeloid-derived suppressor cells in combination with tumor cell vaccination predicts anti-tumor immunity and breast cancer dormancy: An in silico …

R Mehdizadeh, SP Shariatpanahi, B Goliaei… - Scientific reports, 2023 - nature.com
Among the different breast cancer subsets, triple-negative breast cancer (TNBC) has the
worst prognosis and limited options for targeted therapies. Immunotherapies are emerging …

Cancerous tumor controlled treatment using search heuristic (GA)-based sliding mode and synergetic controller

F Subhan, MA Aziz, IU Khan, M Fayaz, M Wozniak… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is basically a tough condition on a patient's body where cell grows
uncontrollably. Normal cells are affected, which destroys the health of the patient. The main …

A mathematical model of breast tumor progression based on immune infiltration

N Mohammad Mirzaei, S Su, D Sofia… - Journal of Personalized …, 2021 - mdpi.com
Breast cancer is the most prominent type of cancer among women. Understanding the
microenvironment of breast cancer and the interactions between cells and cytokines will …

Dynamical behavior of a cancer growth model with chemotherapy and boosting of the immune system

S Jawad, M Winter, ZASA Rahman, YIA Al-Yasir, A Zeb - Mathematics, 2023 - mdpi.com
In this study, we set up and analyze a cancer growth model that integrates a chemotherapy
drug with the impact of vitamins in boosting and strengthening the immune system. The aim …

A PDE model of breast tumor progression in MMTV-PyMT mice

N Mohammad Mirzaei, Z Tatarova, W Hao… - Journal of Personalized …, 2022 - mdpi.com
The evolution of breast tumors greatly depends on the interaction network among different
cell types, including immune cells and cancer cells in the tumor. This study takes advantage …

Mathematical modeling of tumor growth and treatment: Triple negative breast cancer

HC Wei - Mathematics and Computers in Simulation, 2023 - Elsevier
In this study, a mathematical model of triple negative breast cancer (TNBC) with checkpoint
inhibitor immunotherapy is proposed. The mathematical model includes interactions …

Personalized immunotherapy treatment strategies for a dynamical system of chronic myelogenous leukemia

PA Valle, LN Coria, C Plata - Cancers, 2021 - mdpi.com
Simple Summary As computer performance continues to grow at more affordable costs,
mathematical modelling and in silico experimentation begin to play a larger role in …

Mathematical modeling approach of cancer immunoediting reveals new insights in targeted-therapy and timing plan of cancer treatment

M Ghanizadeh, SP Shariatpanahi, B Goliaei… - Chaos, Solitons & …, 2021 - Elsevier
Mathematical modeling was shown to be a powerful tool to describe immune system-cancer
dynamics and specifically immunoediting. Here, we used a system of two ordinary …

[HTML][HTML] A computational probabilistic procedure to quantify the time of breast cancer recurrence after chemotherapy administration

C Burgos, JC Cortés, S Díez-Domingo… - Chaos, Solitons & …, 2024 - Elsevier
We propose a random linear differential equation with jumps to model the dynamics of
breast tumor growth using real patients' data. The model considers the effect of …

A Mathematical Model to Optimize the Neoadjuvant Chemotherapy Treatment Sequence for Triple-Negative Locally Advanced Breast Cancer

JC López-Alvarenga, A Minzoni-Alessio… - Mathematics, 2023 - mdpi.com
Background: Triple-negative locally advanced breast cancer is an aggressive tumor type.
Currently, the standard sequence treatment is applied, administering anthracyclines first and …