Glutathione peroxidases

R Brigelius-Flohé, M Maiorino - … et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
BACKGROUND: With increasing evidence that hydroperoxides are not only toxic but rather
exert essential physiological functions, also hydroperoxide removing enzymes have to be re …

Selenium: an element for life

LH Duntas, S Benvenga - Endocrine, 2015 - Springer
This review aims to illustrate the importance of selenium (Se) for maintenance of overall
health, especially for the thyroid, immunity, and homeostasis. Furthermore, it outlines the …

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

LR Ferguson, H Chen, AR Collins, M Connell… - Seminars in cancer …, 2015 - Elsevier
Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …

Sources and deficiency diseases of mineral nutrients in human health and nutrition: a review

UC Gupta, SC Gupta - Pedosphere, 2014 - Elsevier
Mineral nutrients are fundamentally metals and other inorganic compounds. The life cycle of
these mineral nutrients begins in soil, their primary source. Soil provides minerals to plants …

Selenium and human health: witnessing a Copernican revolution?

E Jablonska, M Vinceti - … of Environmental Science and Health, Part …, 2015 - Taylor & Francis
In humans, selenium was hypothesized to lower the risk of several chronic diseases, mainly
due to the antioxidant activity of selenium-containing proteins. Recent epidemiologic and …

A comprehensive review on the neuropathophysiology of selenium

M Naderi, P Puar, M Zonouzi-Marand… - Science of the Total …, 2021 - Elsevier
As an essential micronutrient, selenium (Se) exerts its biological function as a catalytic entity
in a variety of enzymes. From a toxicological perspective, however, Se can become …

Selenium and its' role in the maintenance of genomic stability

LR Ferguson, N Karunasinghe, S Zhu… - … research/fundamental and …, 2012 - Elsevier
Selenium (Se) is an essential micronutrient for humans, acting as a component of the
unusual amino acids, selenocysteine (Se-Cys) and selenomethionine (Se-Met). Where Se …

Relatively high mortality risk in elderly Swedish subjects with low selenium status

U Alehagen, P Johansson, M Björnstedt… - European Journal of …, 2016 - nature.com
Results: The mean serum Se level of the study population (n= 668) was 67.1 μg/l,
corresponding to relatively low Se intake. After adjustment for male gender, smoking …

[HTML][HTML] Cerebrospinal fluid of newly diagnosed amyotrophic lateral sclerosis patients exhibits abnormal levels of selenium species including elevated selenite

M Vinceti, N Solovyev, J Mandrioli, CM Crespi… - Neurotoxicology, 2013 - Elsevier
Exposure to selenium, and particularly to its inorganic forms, has been hypothesized as a
risk factor for amyotrophic lateral sclerosis (ALS), a fast progressing motor neuron disease …

Does a role for selenium in DNA damage repair explain apparent controversies in its use in chemoprevention?

S Bera, VD Rosa, W Rachidi, AM Diamond - Mutagenesis, 2013 - academic.oup.com
The trace element selenium is an essential micronutrient that has received considerable
attention for its potential use in the prevention of cancer. In spite of this interest, the …