An ever-increasing demand for novel antimicrobials to treat life-threatening infections
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …

Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Notorious bacterial biofilms are becoming severe threats to public health worldwide. As the
important component in biofilm extracellular polymeric substances (EPS), extracellular DNA …

Antimicrobial resistance is directly responsible for more deaths per year than either
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …

Pseudomonas aeruginosa biofilms are composed of exopolysaccharides (EPS), exogenous
DNA, and proteins that hold these communities together. P. aeruginosa produces lectins …

Biofilm formation significantly contributes to microbial survival in hostile environments and it
is currently considered a key virulence factor for pathogens responsible for serious chronic …

The chronic infections by pathogenic Pseudomonas aeruginosa (P. aeruginosa) remain to
be properly addressed. In particular, for drug‐resistant strains, limited medication is …

Multidrug‐resistant Pseudomonas aeruginosa (MDR‐P. aeruginosa) cannot be extirpated
with any of the antipseudomonal antibiotics available in clinic because P. aeruginosa exhibit …

The public view on antibiotics as reliable medicines changed when reports about “resistant
superbugs” appeared in the news. While reasons for this resistance development are easily …

By forming extended hydrogen-bond networks, the contribution of hydroxyl groups to affinity
can reach several orders of magnitude. However, because of the high directionality of their …