All soluble proteins populate conformational ensembles that together constitute the native
state. Their fluctuations in water are intrinsic thermodynamic phenomena, and the …

Highlights•Search strategies of current protein–protein docking algorithms were
reviewed.•Challenges and future directions of established approaches were discussed.•Post …

Abstract The HDOCK server (http://hdock. phys. hust. edu. cn/) is a highly integrated suite of
homology search, template-based modeling, structure prediction, macromolecular docking …

Protein–protein and protein–DNA/RNA interactions play a fundamental role in a variety of
biological processes. Determining the complex structures of these interactions is valuable, in …

Protein–protein docking is an important computational tool for predicting protein–protein
interactions. With the rapid development of proteomics projects, more and more …

Deciphering the structural determinants of protein–protein interactions (PPIs) is essential to
gain a deep understanding of many important biological functions in the living cells …

Protein–protein and protein–DNA/RNA interactions are involved in many cellular processes.
Therefore, determining their complex structures at the atomic level is valuable to gain …

Short peptides play important roles in cellular processes including signal transduction,
immune response and transcription regulation. Correct identification of the peptide binding …

Rationale: Trimeric intracellular cation (TRIC)-A and B are distributed to endoplasmic
reticulum/sarcoplasmic reticulum intracellular Ca2+ stores. The crystal structure of TRIC has …

The improvement and maintenance of enzymatic activities represent major challenges.
However, to address these we developed novel biomimetic polysaccharide hyaluronan (Hn) …