The spirooxindole system is the core structure of a variety of medicinal agents and natural
products. 1, 2 In fact, spirooxindole derivatives have been described with different biological …

N-Acyliminium ions are powerful reactive species for the formation of carbon–carbon and
carbon–heteroatom bonds. Strategies relying on intramolecular reactions of N-acyliminium …

Development of an acid catalyzed, intramolecular benzannulation of indoles for the
synthesis of functionalized carbazoles has been reported. The indole appended Z-enoate …

Ynamides, as versatile synthetic precursors, have attracted much attention from synthetic
chemists and sparked the development of a number of methodologies for the construction of …

Inactivation of the p53 tumor suppressor protein by interaction with murine double minute
(MDM) proteins, MDM2 and MDMX, is a common event in human tumors expressing wild …

An expedient diastereoselective synthesis of highly functionalized indolo [2, 3-α]
quinolizidines adopting a cis H2/H12b geometry has been realized by a Pictet− Spengler …

Abstract N‐Fluorobenzenesulfonimide (NFSI), one of the most popular fluorinating agents in
organic synthesis, was used as a ligand of silver triflate (AgOTf) to assist the trapping of the …

The review summarizes data published in the last decade on the reactions of organic
compounds involving N-acyliminium ions, including intramolecular arylation (cyclization) …

Starting from (S)-tryptophanol, a formal synthesis of ent-rhynchophylline and ent-
isorhynchophylline, involving stereoselective cyclocondensation, spirocyclization, and …

The development of a versatile method for the synthesis of spirocyclic pyrrolidinoindolines is
discussed. Treatment of N-acyltryptamines with trifluoromethanesulfonic anhydride–2 …