Environmental determinants of cardiovascular disease: lessons learned from air pollution

SG Al-Kindi, RD Brook, S Biswal… - Nature Reviews …, 2020 - nature.com
Air pollution is well recognized as a major risk factor for chronic non-communicable
diseases and has been estimated to contribute more to global morbidity and mortality than …

Environmental risk factors and cardiovascular diseases: a comprehensive expert review

T Münzel, O Hahad, M Sørensen… - Cardiovascular …, 2022 - academic.oup.com
Non-communicable diseases (NCDs) are fatal for more than 38 million people each year
and are thus the main contributors to the global burden of disease accounting for 70% of …

Air Pollution and Cardiovascular Disease: JACC State-of-the-Art Review

S Rajagopalan, SG Al-Kindi, RD Brook - Journal of the American College of …, 2018 - jacc.org
Abstract Fine particulate matter< 2.5 μm (PM2. 5) air pollution is the most important
environmental risk factor contributing to global cardiovascular (CV) mortality and disability …

[HTML][HTML] Foam cells in atherosclerosis: novel insights into its origins, consequences, and molecular mechanisms

Y Gui, H Zheng, RY Cao - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Foam cells play a vital role in the initiation and development of atherosclerosis. This review
aims to summarize the novel insights into the origins, consequences, and molecular …

Environmental determinants of cardiovascular disease

A Bhatnagar - Circulation research, 2017 - Am Heart Assoc
Many features of the environment have been found to exert an important influence on
cardiovascular disease (CVD) risk, progression, and severity. Changes in the environment …

Effects of gaseous and solid constituents of air pollution on endothelial function

T Münzel, T Gori, S Al-Kindi, J Deanfield… - European heart …, 2018 - academic.oup.com
Ambient air pollution is a leading cause of non-communicable disease globally. The largest
proportion of deaths and morbidity due to air pollution is now known to be due to …

Effect of particulate matter air pollution on cardiovascular oxidative stress pathways

X Rao, J Zhong, RD Brook… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Particulate matter (PM) air pollution is a leading cause of global cardiovascular
morbidity and mortality. Understanding the biological action of PM is of particular importance …

Environmental stressors and cardio-metabolic disease: part II–mechanistic insights

T Münzel, M Sørensen, T Gori, FP Schmidt… - European heart …, 2017 - academic.oup.com
Environmental factors can act as facilitators of chronic non-communicable diseases.
Ambient noise and air pollution collectively outrank all other environmental risk factors in …

[HTML][HTML] Trimethylamine N-oxide promotes atherosclerosis via CD36-dependent MAPK/JNK pathway

J Geng, C Yang, B Wang, X Zhang, T Hu, Y Gu… - Biomedicine & …, 2018 - Elsevier
Background Many studies have identified trimethylamine N-oxide (TMAO) as a new risk
factor of cardiovascular diseases. It has been suggested that TMAO promotes …

[HTML][HTML] Oxidative stress pathways of air pollution mediated toxicity: Recent insights

RS Gangwar, GH Bevan, R Palanivel, L Das… - Redox biology, 2020 - Elsevier
Ambient air pollution is a leading environmental cause of morbidity and mortality globally
with most of the outcomes of cardiovascular origin. While numerous mechanisms are …