[HTML][HTML] Depression and adult neurogenesis: Positive effects of the antidepressant fluoxetine and of physical exercise

L Micheli, M Ceccarelli, G D'Andrea, F Tirone - Brain research bulletin, 2018 - Elsevier
Of wide interest for health is the relation existing between depression, a very common
psychological illness, accompanied by anxiety and reduced ability to concentrate, and adult …

Bridging animal and human models of exercise-induced brain plasticity

MW Voss, C Vivar, AF Kramer, H van Praag - Trends in cognitive sciences, 2013 - cell.com
Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …

Neurogenesis in the embryonic and adult brain: same regulators, different roles

N Urbán, F Guillemot - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Neurogenesis persists in adult mammals in specific brain areas, known as neurogenic
niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological …

[HTML][HTML] Relationships of peripheral IGF-1, VEGF and BDNF levels to exercise-related changes in memory, hippocampal perfusion and volumes in older adults

A Maass, S Düzel, T Brigadski, M Goerke, A Becke… - Neuroimage, 2016 - Elsevier
Animal models point towards a key role of brain-derived neurotrophic factor (BDNF), insulin-
like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in mediating …

Physical exercise, neuroplasticity, spatial learning and memory

RC Cassilhas, S Tufik, MT De Mello - Cellular and molecular life sciences, 2016 - Springer
There has long been discussion regarding the positive effects of physical exercise on brain
activity. However, physical exercise has only recently begun to receive the attention of the …

The role of Insulin-Like Growth Factor 1 (IGF-1) in brain development, maturation and neuroplasticity

AH Dyer, C Vahdatpour, A Sanfeliu, D Tropea - Neuroscience, 2016 - Elsevier
Abstract Insulin-Like Growth Factor 1 (IGF-1) is a phylogenetically ancient neurotrophic
hormone with crucial roles to play in CNS development and maturation. Recently, IGF-1 has …

The many faces of insulin-like peptide signalling in the brain

AM Fernandez, I Torres-Alemán - Nature Reviews Neuroscience, 2012 - nature.com
Central and peripheral insulin-like peptides (ILPs), which include insulin, insulin-like growth
factor 1 (IGF1) and IGF2, exert many effects in the brain. Through their actions on brain …

Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males

ÉW Griffin, S Mullally, C Foley, SA Warmington… - Physiology & …, 2011 - Elsevier
Physical activity has been reported to improve cognitive function in humans and rodents,
possibly via a brain-derived neurotrophic factor (BDNF)-regulated mechanism. In this study …

Acute exercise improves motor memory: exploring potential biomarkers

K Skriver, M Roig, J Lundbye-Jensen, J Pingel… - Neurobiology of learning …, 2014 - Elsevier
We have recently shown that a single bout of acute cardiovascular exercise improves motor
skill learning through an optimization of long-term motor memory. Here we expand this …

Energy intake and exercise as determinants of brain health and vulnerability to injury and disease

MP Mattson - Cell metabolism, 2012 - cell.com
Evolution favored individuals with superior cognitive and physical abilities under conditions
of limited food sources, and brain function can therefore be optimized by intermittent dietary …