Imaging techniques permit the study of the molecular interactions that underlie health and
disease. Each imaging technique collects unique chemical information about the cellular …

Contrast-enhanced magnetic resonance imaging (MRI) is an indispensable tool for
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …

Manganese (Mn) is an essential metal that can be neurotoxic when elevated exposition
occurs leading to parkinsonian-like syndromes. Mutations in the Slc30a10 gene have been …

Manganese is a neurotoxic element that leads to severe neurological disorders when
excessive exposure occurs, mainly in occupational settings, but that can also lead to more …

Abstract β-cells, located in the islets of the pancreas, are responsible for production and
secretion of insulin and play a crucial role in blood sugar regulation. Pathologic β-cells often …

Non-invasive imaging of β-cells represents a desirable preclinical and clinical tool to monitor
the change of β-cell mass and the loss of function during pre-diabetic stages. Although it is …

Manganese serves as a cofactor to a variety of proteins necessary for proper bodily
development and function. However, an overabundance of Mn in the brain can result in …

Purpose: X‐ray fluorescence computed tomography (XFCT) is an emerging imaging
modality that maps the three‐dimensional distribution of elements, generally metals, inex …

This review demonstrates advances in XRF instrumentation, techniques and data
processing algorithms published during the last year. Pixellated detectors and EDXRF …

A non-invasive method to image the mass and/or function of human pancreatic islets is
needed to monitor the progression of diabetes, and the effect of therapeutic interventions. As …