[HTML][HTML] Breaching the Barrier: Investigating Initial Herpes Simplex Viral Infection and Spread in Human Skin and Mucosa
H Rana, NR Truong, DR Sirimanne, AL Cunningham - Viruses, 2024 - pmc.ncbi.nlm.nih.gov
Herpes simplex virus (HSV) is sexually transmitted via the anogenital mucosa where it
initially infects epidermal keratinocytes and mononuclear phagocytes (MNPs). It then …
initially infects epidermal keratinocytes and mononuclear phagocytes (MNPs). It then …
Short‐form thymic stromal lymphopoietin (sfTSLP) restricts herpes simplex virus infection of human primary keratinocytes
J Zeitvogel, K Döhner, I Klug, T Richardo… - Journal of Medical …, 2024 - Wiley Online Library
Eczema herpeticum (EH) is a disseminated severe herpes simplex virus type 1 (HSV‐1)
infection that mainly occurs in a subset of patients suffering from atopic dermatitis (AD). EH is …
infection that mainly occurs in a subset of patients suffering from atopic dermatitis (AD). EH is …
Interferon inhibits the release of herpes simplex virus-1 from the axons of sensory neurons
K Danastas, G Guo, J Merjane, N Hong, A Larsen… - Mbio, 2023 - Am Soc Microbiol
ABSTRACT Herpes simplex virus-1 (HSV-1) has evolved mechanisms to evade the host
immune system and limit the antiviral effects induced by interferon (IFN) produced by local …
immune system and limit the antiviral effects induced by interferon (IFN) produced by local …
Genome-wide CRISPR screens identify CLC-2 as a drug target for anti-herpesvirus therapy: tackling herpesvirus drug resistance
F Yang, N Wei, S Cai, J Liu, Q Lan, H Zhang… - Science China Life …, 2024 - Springer
The emergence of drug resistance to virus (ie, acyclovir (ACV) to herpesviruses) has been
termed one of the common clinical issues, emphasizing the discovery of new antiviral …
termed one of the common clinical issues, emphasizing the discovery of new antiviral …
Downregulation of endogenous nectin1 in human keratinocytes by herpes simplex virus 1 glycoprotein D excludes superinfection but does not affect NK cell function
J Kite, M Hill, N Preston, A Rubina… - Journal of General …, 2024 - microbiologyresearch.org
Many viruses downregulate their cognate receptors, facilitating virus replication and
pathogenesis via processes that are not yet fully understood. In the case of herpes simplex …
pathogenesis via processes that are not yet fully understood. In the case of herpes simplex …
Interactions between Herpes Simplex Virus, intraepidermal nerves and epidermal Langerhans and dendritic cells within human skin
JJ Herbert - 2023 - ses.library.usyd.edu.au
Herpes Simplex virus types 1 and 2 (HSV-1 and-2) are prevalent lifelong infections globally,
causing serious complications and predisposing to HIV acquisition. HSV-1 infection of the …
causing serious complications and predisposing to HIV acquisition. HSV-1 infection of the …
[PDF][PDF] The role of the nectin1 receptor in HSV1 infection of human keratinocytes
J Kite - 2023 - openresearch.surrey.ac.uk
Primary HSV1 infection occurs in the keratinocytes that form the stratified epithelium of
human skin and mucosa. Despite HSV1 entry being a well studied aspect of the viral …
human skin and mucosa. Despite HSV1 entry being a well studied aspect of the viral …
[PDF][PDF] Characterisation of Virus-Induced Cytoplasmic Domains using the Herpes Simplex Virus Protein UL46
DM Perry - 2023 - openresearch.surrey.ac.uk
Cell biological studies of a range of viruses have led to the discovery of virus-induced
cellular compartments. In the case of herpes simplex virus type 1 (HSV-1), novel and …
cellular compartments. In the case of herpes simplex virus type 1 (HSV-1), novel and …
La infección productiva por Herpes Simplex Tipo 1 altera la biogénesis mitocondrial en células epiteliales humanas: Productive Herpes Simplex Type 1 infection …
JE Rosas, BO Barría - Revista de Estudiantes de Medicina del Sur, 2024 - rems.ufro.cl
Introducción: La infección por HSV-1 ha sido estudiada en neuronas, donde se ha
observado una alteración de las vías de señalización celular durante la infección, utilizando …
observado una alteración de las vías de señalización celular durante la infección, utilizando …