Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Monitoring of cerebrovascular autoregulation: facts, myths, and missing links

M Czosnyka, K Brady, M Reinhard, P Smielewski… - Neurocritical care, 2009 - Springer
The methods for continuous assessment of cerebral autoregulation using correlation, phase
shift, or transmission (either in time-or frequency-domain) were introduced a decade ago …

Transcranial Doppler for evaluation of cerebral autoregulation

RB Panerai - Clinical autonomic research, 2009 - Springer
Transcranial Doppler ultrasound (TCD) can measure cerebral blood flow velocity in the main
intracranial vessels non-invasively and with high accuracy. Combined with the availability of …

Impaired autoregulation of cerebral blood flow during rewarming from hypothermic cardiopulmonary bypass and its potential association with stroke

B Joshi, K Brady, J Lee, B Easley… - Anesthesia & …, 2010 - journals.lww.com
BACKGROUND: Patient rewarming after hypothermic cardiopulmonary bypass (CPB) has
been linked to brain injury after cardiac surgery. In this study, we evaluated whether cooling …

Quantification of dynamic cerebral autoregulation: welcome to the jungle!

P Brassard, MA Roy, JS Burma, L Labrecque… - Clinical Autonomic …, 2023 - Springer
Purpose Patients with dysautonomia often experience symptoms such as dizziness,
syncope, blurred vision and brain fog. Dynamic cerebral autoregulation, or the ability of the …

Near-infrared spectroscopy can monitor dynamic cerebral autoregulation in adults

LA Steiner, D Pfister, SP Strebel, D Radolovich… - Neurocritical care, 2009 - Springer
Objective To study the correlation between a dynamic index of cerebral autoregulation
assessed with blood flow velocity (FV) using transcranial Doppler, and a tissue oxygenation …

The relationship between cerebral blood flow autoregulation and cerebrovascular pressure reactivity after traumatic brain injury

KP Budohoski, M Czosnyka, N de Riva… - …, 2012 - journals.lww.com
BACKGROUND: Cerebrovascular pressure reactivity is the principal mechanism of cerebral
autoregulation. Assessment of cerebral autoregulation can be performed by using the mean …

Cerebral autoregulation-oriented therapy at the bedside

L Rivera-Lara, A Zorrilla-Vaca, RG Geocadin… - …, 2017 - ingentaconnect.com
This comprehensive review summarizes the evidence regarding use of cerebral
autoregulation-directed therapy at the bedside and provides an evaluation of its impact on …

Continuous assessment of cerebral autoregulation with near-infrared spectroscopy in adults after subarachnoid hemorrhage

C Zweifel, G Castellani, M Czosnyka, E Carrera… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—In patients with subarachnoid hemorrhage, the assessment of
cerebral autoregulation aids in prognosis as well as detection of vasospasm. Mx is a …

Continuous time-domain monitoring of cerebral autoregulation in neurocritical care

C Zweifel, C Dias, P Smielewski, M Czosnyka - Medical engineering & …, 2014 - Elsevier
Integration of various brain signals can be used to determine cerebral autoregulation in
neurocritical care patients to guide clinical management and to predict outcome. In this …