Role and mechanism of LAIR-1 in the development of autoimmune diseases, tumors, and malaria: a review

N Guo, K Zhang, X Gao, M Lv, J Luan, Z Hu, A Li… - Current Research in …, 2020 - Elsevier
The levels of leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1), a type I
transmembrane glycoprotein broadly expressed on the majority of hematopoietic cells, such …

Entire expressed peripheral blood transcriptome in pediatric severe malarial anemia

SB Anyona, Q Cheng, SA Wasena, SW Osata… - Nature …, 2024 - nature.com
This study on severe malarial anemia (SMA: Hb< 6.0 g/dL), a leading global cause of
childhood morbidity and mortality, compares the entire expressed whole blood host …

Malaria hospitalisation in East Africa: age, phenotype and transmission intensity

A Kamau, RS Paton, S Akech, A Mpimbaza… - BMC medicine, 2022 - Springer
Background Understanding the age patterns of disease is necessary to target interventions
to maximise cost-effective impact. New malaria chemoprevention and vaccine initiatives …

Human NCR3 gene variants rs2736191 and rs11575837 alter longitudinal risk for development of pediatric malaria episodes and severe malarial anemia

CO Onyango, Q Cheng, EO Munde, E Raballah… - BMC genomics, 2023 - Springer
Background Plasmodium falciparum malaria is a leading cause of pediatric morbidity and
mortality in holoendemic transmission areas. Severe malarial anemia [SMA, hemoglobin …

Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia

E Raballah, SB Anyona, Q Cheng… - Experimental …, 2022 - journals.sagepub.com
Severe malarial anemia (SMA) is a leading cause of childhood morbidity and mortality in
holoendemic Plasmodium falciparum transmission regions. To gain enhanced …

Nonsynonymous amino acid changes in the α-chain of complement component 5 influence longitudinal susceptibility to Plasmodium falciparum infections and severe …

E Raballah, K Wilding, SB Anyona, EO Munde… - Frontiers in …, 2022 - frontiersin.org
Background: Severe malarial anemia (SMA; Hb< 5.0 g/dl) is a leading cause of childhood
morbidity and mortality in holoendemic Plasmodium falciparum transmission regions such …

Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden …

LE Kisia, Q Cheng, E Raballah, EO Munde… - Tropical Medicine and …, 2022 - Springer
Plasmodium falciparum infections remain among the leading causes of morbidity and
mortality in holoendemic transmission areas. Located within region 5q31. 1, the colony …

LAIR1 prevents excess inflammatory tissue damage in S. aureus skin infection and Cutaneous T-cell Lymphoma

HK Dorando, EC Mutic, KL Tomaszewski, L Tian… - bioRxiv, 2024 - biorxiv.org
Patients with cutaneous T cell lymphoma (CTCL) experience high morbidity and mortality
due to S. aureus skin infections and sepsis, but the causative immune defect is unclear. We …

Epigenetic regulation of Leukocyte associated immunoglobulin-like receptors 1 and 2 by interferon signaling in macrophages and T cells

HK Dorando, EC Mutic, JY Li, EP Perrin, M Wurtz… - bioRxiv, 2023 - biorxiv.org
Background: Inhibitory immune receptors are important for maintaining immune
homeostasis. We recently identified epigenetic alterations in two members of this group …

[图书][B] Studies on the Leukocyte-Associated Ig-Like Inhibitory Receptor-1 Signaling Pathway in T Lymphocytes

C Zacheaus - 2023 - search.proquest.com
Inflammation is a natural process in which the immune system concertedly responds to
pathogens and abnormal cell growth to protect the host. For an efficient/effective immune …