This study on severe malarial anemia (SMA: Hb< 6.0 g/dL), a leading global cause of childhood morbidity and mortality, compares the entire expressed whole blood host …
Background Understanding the age patterns of disease is necessary to target interventions to maximise cost-effective impact. New malaria chemoprevention and vaccine initiatives …
CO Onyango, Q Cheng, EO Munde, E Raballah… - BMC genomics, 2023 - Springer
Background Plasmodium falciparum malaria is a leading cause of pediatric morbidity and mortality in holoendemic transmission areas. Severe malarial anemia [SMA, hemoglobin …
Severe malarial anemia (SMA) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission regions. To gain enhanced …
Background: Severe malarial anemia (SMA; Hb< 5.0 g/dl) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission regions such …
Plasmodium falciparum infections remain among the leading causes of morbidity and mortality in holoendemic transmission areas. Located within region 5q31. 1, the colony …
HK Dorando, EC Mutic, KL Tomaszewski, L Tian… - bioRxiv, 2024 - biorxiv.org
Patients with cutaneous T cell lymphoma (CTCL) experience high morbidity and mortality due to S. aureus skin infections and sepsis, but the causative immune defect is unclear. We …
HK Dorando, EC Mutic, JY Li, EP Perrin, M Wurtz… - bioRxiv, 2023 - biorxiv.org
Background: Inhibitory immune receptors are important for maintaining immune homeostasis. We recently identified epigenetic alterations in two members of this group …
Inflammation is a natural process in which the immune system concertedly responds to pathogens and abnormal cell growth to protect the host. For an efficient/effective immune …