The pathogenesis of obesity

SM Oussaada, KA Van Galen, MI Cooiman… - Metabolism, 2019 - Elsevier
Body fat mass increases when energy intake exceeds energy expenditure. In the long term,
a positive energy balance will result in obesity. The worldwide prevalence of obesity has …

[HTML][HTML] Worldwide flavor enhancer monosodium glutamate combined with high lipid diet provokes metabolic alterations and systemic anomalies: An overview

A Banerjee, S Mukherjee, BK Maji - Toxicology Reports, 2021 - Elsevier
In this fast-food era, people depend on ready-made foods and engage in minimal physical
activities that ultimately change their food habits. Majorities of such foods have harmful …

FGF21 is a sugar-induced hormone associated with sweet intake and preference in humans

S Søberg, CH Sandholt, NZ Jespersen, U Toft… - Cell metabolism, 2017 - cell.com
The liking and selective ingestion of palatable foods—including sweets—is biologically
controlled, and dysfunction of this regulation may promote unhealthy eating, obesity, and …

Physiology of the tongue with emphasis on taste transduction

ME Doyle, HU Premathilake, Q Yao… - Physiological …, 2023 - journals.physiology.org
The tongue is a complex multifunctional organ that interacts and senses both interoceptively
and exteroceptively. Although it is easily visible to almost all of us, it is relatively …

Inflammation arising from obesity reduces taste bud abundance and inhibits renewal

A Kaufman, E Choo, A Koh, R Dando - PLoS biology, 2018 - journals.plos.org
Despite evidence that the ability to taste is weakened by obesity and can be rescued with
weight loss intervention, few studies have investigated the molecular effects of obesity on …

High dietary sugar reshapes sweet taste to promote feeding behavior in Drosophila melanogaster

CE May, A Vaziri, YQ Lin, O Grushko, M Khabiri… - Cell reports, 2019 - cell.com
Recent studies find that sugar tastes less intense to humans with obesity, but whether this
sensory change is a cause or a consequence of obesity is unclear. To tackle this question …

Higher sensitivity to sweet and salty taste in obese compared to lean individuals

S Hardikar, R Höchenberger, A Villringer, K Ohla - Appetite, 2017 - Elsevier
Although putatively taste has been associated with obesity as one of the factors governing
food intake, previous studies have failed to find a consistent link between taste perception …

Physiological mechanisms by which non-nutritive sweeteners may impact body weight and metabolism

MV Burke, DM Small - Physiology & behavior, 2015 - Elsevier
Evidence linking sugar-sweetened beverage (SSB) consumption to weight gain and other
negative health outcomes has prompted many individuals to resort to artificial, non-nutritive …

[HTML][HTML] Sweet taste exposure and the subsequent acceptance and preference for sweet taste in the diet: systematic review of the published literature

KM Appleton, H Tuorila, EJ Bertenshaw… - The American Journal of …, 2018 - Elsevier
Background There are consistent, evidence-based global public health recommendations to
reduce intakes of free sugars. However, the corresponding evidence for recommending …

Nutrition and taste and smell dysfunction

JC Kershaw, RD Mattes - World journal of otorhinolaryngology-head …, 2018 - mednexus.org
Food selection plays a pivotal role in maintaining adequate nutrient intake, thus elucidating
drivers of food choice is a meaningful strategy to maintain health and manage disease …