Lensless imaging and sensing

A Ozcan, E McLeod - Annual review of biomedical engineering, 2016 - annualreviews.org
High-resolution optical microscopy has traditionally relied on high-magnification and high–
numerical aperture objective lenses. In contrast, lensless microscopy can provide high …

Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy

A Greenbaum, W Luo, TW Su, Z Göröcs, L Xue… - Nature …, 2012 - nature.com
We discuss unique features of lens-free computational imaging tools and report some of
their emerging results for wide-field on-chip microscopy, such as the achievement of a …

Optical imaging techniques for point-of-care diagnostics

H Zhu, SO Isikman, O Mudanyali, A Greenbaum… - Lab on a Chip, 2013 - pubs.rsc.org
Improving access to effective and affordable healthcare has long been a global endeavor. In
this quest, the development of cost-effective and easy-to-use medical testing equipment that …

Smartphone‐based clinical diagnostics: towards democratization of evidence‐based health care

I Hernández‐Neuta, F Neumann… - Journal of internal …, 2019 - Wiley Online Library
Recent advancements in bioanalytical techniques have led to the development of novel and
robust diagnostic approaches that hold promise for providing optimal patient treatment …

Nanomedicine: application areas and development prospects

H Boulaiz, PJ Alvarez, A Ramirez, JA Marchal… - International journal of …, 2011 - mdpi.com
Nanotechnology, along with related concepts such as nanomaterials, nanostructures and
nanoparticles, has become a priority area for scientific research and technological …

Unconventional methods of imaging: computational microscopy and compact implementations

E McLeod, A Ozcan - Reports on Progress in Physics, 2016 - iopscience.iop.org
In the past two decades or so, there has been a renaissance of optical microscopy research
and development. Much work has been done in an effort to improve the resolution and …

On-chip biomedical imaging

Z Göröcs, A Ozcan - IEEE reviews in biomedical engineering, 2012 - ieeexplore.ieee.org
Lab-on-a-chip systems have been rapidly emerging to pave the way toward ultra-compact,
efficient, mass producible and cost-effective biomedical research and diagnostic tools …

Simultaneous detection of cell-secreted TNF-α and IFN-γ using micropatterned aptamer-modified electrodes

Y Liu, T Kwa, A Revzin - Biomaterials, 2012 - Elsevier
Cellular production of such cytokines as interferon (IFN)-γ and tumor necrosis factor (TNF)-α
is used to determine disease-specific immune responses and may be used to diagnose …

Microfluidics on lensless, semiconductor optical image sensors: challenges and opportunities for democratization of biosensing at the micro-and nano-scale

X Hu, R Abbasi, S Wachsmann-Hogiu - Nanophotonics, 2023 - degruyter.com
Optical image sensors are 2D arrays of pixels that integrate semiconductor photodiodes and
field effect transistors for efficient photon conversion and processing of generated electrons …

An aptasensor for electrochemical detection of tumor necrosis factor in human blood

Y Liu, Q Zhou, A Revzin - Analyst, 2013 - pubs.rsc.org
Electrochemical aptasensors can detect disease markers such as cytokines to provide point-
of-care diagnosis that is low-cost, rapid, specific and sensitive. Herein, we describe the …