Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

The skin, being the barrier organ of the body, is constitutively exposed to various stimuli
impacting its morphology and function. Senescent cells have been found to accumulate with …

The skin is the largest organ and has a key protective role. Similar to any other tissue, the
skin is influenced not only by intrinsic/chronological aging, but also by extrinsic aging …

The role of the microbiome in human aging is important: the microbiome directly impacts
aging through the gastrointestinal system. However, the microbial impact on skin has yet to …

Skin aging is induced and sustained by chronological aging and photoaging. Aging skin
pigmentation such as mottled pigmentation (senile lentigo) and melasma are typical signs of …

The human skin is exposed daily to different environmental factors such as air pollutants and
ultraviolet (UV) light. Air pollution is considered a harmful environmental risk to human skin …

Senolytics are a category of drugs that reduce the impact of cellular senescence, an effect
associated with a range of chronic and age‐related diseases. Since the discovery of the first …

Abstract Age-related Macular Degeneration (AMD), a blinding eye disease, is characterized
by pathological protein-and lipid-rich drusen deposits underneath the retinal pigment …

In an aging society, unveiling new anti-aging strategies to prevent and combat aging-related
diseases is of utmost importance. Mitochondria are the primary ATP production sites and key …

Human skin aging is a natural phenomenon that results from continuous exposure to
intrinsic (time, genetic factors, hormones) as well as extrinsic factors (UV exposure, pollution …