Hypoxia is an essential hallmark of several serious diseases such as cardiovascular and
metabolic disorders and cancer. A decline in the tissue oxygen level induces hypoxic …

Myocardial infarctions are one of the most common forms of cardiac injury and death
worldwide. Infarctions cause immediate necrosis in a localized region of the myocardium …

Impaired wound healing in patients with type 2 diabetes (DM2) is characterized by chronic
inflammation, which delays wound closure. Specialized pro-resolving lipid mediators …

Despite the strong evidence for the immunomodulatory activity of mesenchymal stromal cells
(MSCs), clinical trials have so far failed to clearly show benefit, likely reflecting …

Extracellular vesicles (EVs) represent a diverse group of small membrane-encapsulated
particles involved in cell–cell communication, but the technologies to characterize EVs are …

Pathological reprogramming of cardiomyocyte and fibroblast proteome landscapes drive the
initiation and progression of cardiac fibrosis. Although the secretome of dysfunctional …

Myocardial infarctions locally deprive myocardium of oxygenated blood and cause
immediate cardiac myocyte necrosis. Irreparable myocardium is then replaced with a scar …

Non‐viral vectors represent versatile and immunologically safer alternatives for nucleic acid
delivery. Nanoneedles and high‐aspect ratio nanostructures are unconventional but …

Cardiac fibrosis is insidious, accelerating cardiovascular diseases, heart failure, and death.
With a notable lack of effective therapies, advances in both understanding and targeted …

Cardiovascular diseases (CVDs), which encompass a myriad of pathological conditions that
affect the heart and/or the blood vessels, remain the major cause of morbidity and mortality …