ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

CAR T cells for brain tumors: Lessons learned and road ahead

D Akhavan, D Alizadeh, D Wang, MR Weist… - Immunological …, 2019 - Wiley Online Library
Malignant brain tumors, including glioblastoma, represent some of the most difficult to treat
of solid tumors. Nevertheless, recent progress in immunotherapy, across a broad range of …

Fasting-mimicking diet modulates microbiota and promotes intestinal regeneration to reduce inflammatory bowel disease pathology

P Rangan, I Choi, M Wei, G Navarrete, E Guen… - Cell reports, 2019 - cell.com
Dietary interventions are potentially effective therapies for inflammatory bowel diseases
(IBDs). We tested the effect of 4-day fasting-mimicking diet (FMD) cycles on a chronic …

[HTML][HTML] Monoclonal antibody-based molecular imaging strategies and theranostic opportunities

N Dammes, D Peer - Theranostics, 2020 - ncbi.nlm.nih.gov
Molecular imaging modalities hold great potential as less invasive techniques for diagnosis
and management of various diseases. Molecular imaging combines imaging agents with …

PET/MR imaging of inflammation in atherosclerosis

ML Senders, C Calcagno, A Tawakol… - Nature Biomedical …, 2023 - nature.com
Myocardial infarction, stroke, mental disorders, neurodegenerative processes, autoimmune
diseases, cancer and the human immunodeficiency virus impact the haematopoietic system …

Molecular imaging of chimeric antigen receptor T cells by ICOS-ImmunoPET

F Simonetta, IS Alam, JK Lohmeyer, B Sahaf… - Clinical Cancer …, 2021 - AACR
Purpose: Immunomonitoring of chimeric antigen receptor (CAR) T cells relies primarily on
their quantification in the peripheral blood, which inadequately quantifies their …

Theranostic chimeric antigen receptor (CAR)-T cells: Insight into recent trends and challenges in solid tumors

K Kheyrolahzadeh, MR Tohidkia, A Tarighatnia… - Life Sciences, 2023 - Elsevier
Cell therapy has reached significant milestones in various life-threatening diseases,
including cancer. Cell therapy using fluorescent and radiolabeled chimeric antigen receptor …

Antibody fragment and affibody immunoPET imaging agents: radiolabelling strategies and applications

R Fu, L Carroll, G Yahioglu, EO Aboagye… - …, 2018 - Wiley Online Library
Antibodies have long been recognised as potent vectors for carrying diagnostic medical
radionuclides, contrast agents and optical probes to diseased tissue for imaging. The area of …

Application of nanoparticles in the diagnosis of gastrointestinal diseases: a complete future perspective

N Yue, H Xu, J Xu, M Zhu, Y Zhang… - International Journal …, 2023 - Taylor & Francis
The diagnosis of gastrointestinal (GI) diseases currently relies primarily on invasive
procedures like digestive endoscopy. However, these procedures can cause discomfort …

Integrated imaging and molecular analysis to decipher tumor microenvironment in the era of immunotherapy

J Wu, AT Mayer, R Li - Seminars in cancer biology, 2022 - Elsevier
Radiological imaging is an integral component of cancer care, including diagnosis, staging,
and treatment response monitoring. It contains rich information about tumor phenotypes that …