Leveraging laboratory and clinical studies to design effective antibiotic combination therapy

K Davis, T Greenstein, RV Colindres… - Current opinion in …, 2021 - Elsevier
Highlights•The need for effective antibiotic combination therapy will continue to
increase.•Clinical trials have shown mixed results for the superiority of combination …

[HTML][HTML] Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations

E Hansen, J Karslake, RJ Woods, AF Read… - PLoS …, 2020 - journals.plos.org
Standard infectious disease practice calls for aggressive drug treatment that rapidly
eliminates the pathogen population before resistance can emerge. When resistance is …

[HTML][HTML] Effective therapeutic options for melioidosis: Antibiotics versus phage therapy

YM Lim, J Vadivelu, V Mariappan, G Venkatraman… - Pathogens, 2022 - mdpi.com
Melioidosis, also known as Whitmore's disease, is a potentially fatal infection caused by the
Gram-negative bacteria Burkholderia pseudomallei with a mortality rate of 10–50%. The …

Photodynamic inactivation of bacterial carbapenemases restores bacterial carbapenem susceptibility and enhances carbapenem antibiotic effectiveness

Y Feng, A Palanisami, S Ashraf, B Bhayana… - Photodiagnosis and …, 2020 - Elsevier
The global emergence of carbapenemases in bacterial pathogens has rendered many life-
threatening infections untreatable. Even though using carbapenemase inhibitors are a …

Surveilans retrospektif penggunaan antibiotik pada pasien anak dengan luka bakar

ON Putra, ID Saputro, HD Nurhalisa… - Pharmaceutical Journal of …, 2021 - pji.ub.ac.id
Luka bakar merupakan salah satu bentuk trauma dengan tingkat risiko infeksi yang tinggi.
Modalitas utama pada infeksi akibat luka bakar ialah pemberian antibiotik. Tujuan penelitian …

Efficacy of sub-MIC level of meropenem and ciprofloxacin against extensive drug-resistant (XDR) Pseudomonas aeruginosa isolates of diabetic foot ulcer patients

P Srivastava, K Sivashanmugam - Infection, Genetics and Evolution, 2021 - Elsevier
The increasing emergence of extensive drug-resistant bacteria (XDR) among chronic
diabetic foot ulcer patients (DFU) possess serious threat which leads to foot amputation. The …

[HTML][HTML] Microbiota assessment of pediatric simple and complex acute appendicitis

M Kakar, A Reinis, J Kroica, A Engelis, R Broks… - Medicina, 2022 - mdpi.com
Background and Objectives. The aim of this study is to determine the prevailing microbiota in
samples from pediatric patients with acute appendicitis, as well as evaluate the antibacterial …

Systematic Literature Review: Efektivitas Ekstrak Kopi sebagai Antioksidan dalam Mengatasi Photoaging

OL Ratri, TG Ebtavanny, OE Puspita - Pharmaceutical Journal of …, 2021 - pji.ub.ac.id
Aging of the skin due to exposure of UV rays is referred as photoaging. Â Photoaging
causes dry skin, wrinkles, darker skin pigmentation, and reduced skin firmness. The effect of …

Clinical, Molecular Biological, and Microbiological Integrated Investigation in the Case of Paediatric Acute Complicated and Uncomplicated Appendicitis. Doctoral …

M Kakars - 2023 - dspace.rsu.lv
Appendicitis poses a challenge throughout the entire process from diagnosis to effective
treatment in paediatric patients. Considering that non-surgical or conservative treatment is …

Culture based evaluation of microbiota in children with acute appendicitis

J Kroiča, A Reinis, M Kakar, M Delorme… - Proceedings of the …, 2020 - sciendo.com
Treatment strategies for acute uncomplicated appendicitis have evolved and now
conservative antibacterial treatment is recommended over surgical treatment, especially for …