[HTML][HTML] Novel pyrazolo [3, 4-d] pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action

Z Ruzi, K Bozorov, L Nie, J Zhao, HA Aisa - Biomedicine & …, 2022 - Elsevier
Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition,
and mechanisms of action - ScienceDirect Skip to main contentSkip to article Elsevier logo …

Diversity and Biological Activities of Endophytic Fungi from the Flowers of the Medicinal Plant Vernonia anthelmintica

L Niu, N Rustamova, H Ning, P Paerhati, C Lu… - International Journal of …, 2022 - mdpi.com
Secondary metabolites produced by endophytic fungi are an important source of biologically
active compounds. The current research was focused on the biological activities of ethyl …

Endophytic Bacteria Associated with Medicinal Plant Vernonia anthelmintica: Diversity and Characterization

N Rustamova, A Wubulikasimu, N Mukhamedov… - Current …, 2020 - Springer
Increasing evidence shows that endophytic bacteria living inside plant tissue may possess
similar biological activity and produce similar metabolites to their hosts. This study aimed to …

Biological Activity of Endophytic Fungi from the Roots of the Medicinal Plant Vernonia anthelmintica

N Rustamova, Y Gao, Y Zhang, A Yili - Microorganisms, 2020 - mdpi.com
Endophytic fungi were first isolated from the fresh root of the Chinese medicinal plant
Vernonia anthelmintica collected from the Hotan Prefecture within the Xinjiang Autonomous …

Design, synthesis, biological evaluation, and molecular docking of some new Thieno [2, 3-d] pyrimidine derivatives

MS Tolba, AM Sayed, M Sayed, M Ahmed - Journal of Molecular Structure, 2021 - Elsevier
Due to the biological importance of thienopyrimidine derivatives, we present here a synthetic
way for the design of new thienopyrimidines (2‒11) using the precursor 2-(4-Oxo-9-phenyl …

2‐substituted tricyclic oxazolo[5,4‐d]pyrimidine library: Design, synthesis, and cytotoxicity activity

Y Zeng, L Nie, K Bozorov, Z Ruzi… - Journal of …, 2022 - Wiley Online Library
We report the design, synthetic route, and cytotoxicity of a library of 49 newly synthesized
tricyclic oxazolo [5, 4‐d] pyrimidines. The condensed pyrimidinones were constructed from …

[HTML][HTML] Melanin in fungi: advances in structure, biosynthesis, regulation, and metabolic engineering

Y Qin, Y Xia - Microbial Cell Factories, 2024 - pmc.ncbi.nlm.nih.gov
Fungi can synthesize a diverse range of melanins with appropriate physicochemical and
biological characteristics for numerous applications in health, environmental protection …

Design, combinatorial synthesis and cytotoxic activity of 2-substituted furo[2,3-d]pyrimidinone and pyrrolo[2,3-d]pyrimidinone library

B Song, L Nie, K Bozorov, R Kuryazov, J Zhao… - Molecular Diversity, 2023 - Springer
A facile protocol was developed for the combinatorial synthesis of furo [2, 3-d] pyrimidinone
and pyrrolo [2, 3-d] pyrimidinone library via a one-pot condensation, from 2-amino …

Furo[2,3‐d]pyrimidines as Mackinazolinone/Isaindigotone Analogs: Synthesis, Modification, Antitumor Activity, and Molecular Docking Study

B Song, L Nie, K Bozorov, C Niu… - Chemistry & …, 2023 - Wiley Online Library
The chemical transformation of the tricyclic furo [2, 3‐d] pyrimidines was performed under
isosteric and scaffold‐hopping strategies focusing on the synthesis of its arylidene and imine …

Secondary metabolites produced by endophytic Pantoea ananatis derived from roots of Baccharoides anthelmintica and their effect on melanin synthesis in murine …

N Rustamova, K Bobakulov, N Begmatov… - Natural Product …, 2021 - Taylor & Francis
Five indole derivatives, 1 H-indol-7-ol (1), tryptophol (2), 3-indolepropionic acid (3),
tryptophan (4), 3, 3-di (1 H-indol-3-yl) propane-1, 2-diol (5) and two diketopiperazines, cyclo …