Manufacturing process of liposomal Formation: A coarse-grained molecular dynamics simulation

T Duran, AP Costa, J Kneski, X Xu, DJ Burgess… - International Journal of …, 2024 - Elsevier
A method of producing liposomes has been previously developed using a continuous
manufacturing technology that involves a co-axial turbulent jet in co-flow. In this study …

Studying the ssDNA loaded adeno-associated virus aggregation using coarse-grained molecular dynamics simulations

T Duran, S Naik, L Sharifi, WR DiLuzio… - International Journal of …, 2024 - Elsevier
The aggregation of adeno-associated viral (AAV) capsids in an aqueous environment was
investigated via coarse-grained molecular dynamics (CG-MD) simulations. The primary …

Exploring Latent Space for Generating Peptide Analogs Using Protein Language Models

PY Liang, X Huang, T Duran… - … on Bioinformatics and …, 2024 - ieeexplore.ieee.org
Generating peptides with desired properties is crucial for drug discovery and biotechnology.
Traditional sequence-based and structure-based methods often require extensive datasets …

E (3)-invaraint diffusion model for pocket-aware peptide generation

PY Liang, J Bai - arXiv preprint arXiv:2410.21335, 2024 - arxiv.org
Biologists frequently desire protein inhibitors for a variety of reasons, including use as
research tools for understanding biological processes and application to societal problems …

Head-to-head comparison of in vitro and in vivo efficacy of pHLIP-conjugated anti-seed gamma peptide nucleic acids

K Dhuri, T Duran, B Chaudhuri, FJ Slack… - Cell Reports Physical …, 2023 - cell.com
Gamma peptide nucleic acids (γPNAs) have recently garnered attention in diverse
therapeutic and diagnostic applications. Serine and diethylene-glycol-containing γPNAs …