Introduction Chronic constipation is a common disorder with a reported prevalence ranging
from 3% to 27% in the general population. Several management strategies, including …

Chronic noncancer pain is common and use of opioids is increasing. Previously published
guidelines on use of opioids for chronic noncancer pain have been based primarily on …

Financial Disclosure: The funding bodies (ASCRS and SAGES) did not influence the content
of this work and no other specific funding was received from other entities. Dr Keller is a …

Purpose Acute gastrointestinal (GI) dysfunction and failure have been increasingly
recognized in critically ill patients. The variety of definitions proposed in the past has led to …

This publication was approved by both the ASCRS and SAGES executive council and then
peer-reviewed by the Diseases of the Colon & Rectum and Surgical Endoscopy And Other …

Critically ill patients who are subjected to high stress or with severe injury can rapidly break
down their body protein and energy stores. Unless adequate nutrition is provided …

Peripherally acting μ-opioid receptor antagonists methylnaltrexone and alvimopan are a
new class of drugs designed to reverse opioid-induced side-effects on the gastrointestinal …

Background This article describes the second update of a Cochrane review on the
effectiveness of laxatives for the management of constipation in people receiving palliative …

Opioid-induced bowel dysfunction (OIBD) comprises gastrointestinal (GI) symptoms,
including dry mouth, nausea, vomiting, gastric stasis, bloating, abdominal pain, and opioid …

Clinical practice guideline for enhanced recovery after colon and rectal surgery from the
American Society of Colon and Rectal Surgeons (ASCRS) and Society of American …