Overcoming intrinsic and acquired drug resistance is a major challenge in treating cancer
patients because chemoresistance causes recurrence, cancer dissemination and death …

The adenosine triphosphate (ATP)-binding cassette efflux transporter G2 (ABCG2) was
originally discovered in a multidrug-resistant breast cancer cell line. Studies in the past have …

As a result of the association of a common polymorphism (rs2231142, Q141K) in the ATP-
binding cassette G2 (ABCG2) transporter with serum urate concentration in a genome-wide …

Side population (SP) cells are involved in the development of multidrug resistance (MDR) in
human multiple myeloma (MM), due to their cancer stem cell (CSC)‑like phenotypes. ATP …

Spatially resolved transcriptomics (SrT) can investigate organ or tissue architecture from the
angle of gene programs that define their molecular complexity. However, computational …

Cytochrome c oxidase subunit VIc (COX6c) is one of the most important subunits of the
terminal enzyme of the respiratory chain in mitochondria. Numerous studies have …

Cytochrome c oxidase (CcO) is the final oxygen accepting enzyme complex (complex IV) of
the mitochondrial respiratory chain. In contrast to the other complexes (I, II, and III), CcO is …

Mitochondria, independent double-membrane organelles, are intracellular power plants that
feed most eukaryotic cells with the ATP produced via the oxidative phosphorylation …

Objectives The study of sex differences in hyperuricemia can provide not only a theoretical
basis for this clinical phenomenon but also new therapeutic targets for urate-lowering …

Uterine cancers are among the most prevalent gynecological malignancies, and
endometrial cancer (EC) is the most common in this group. This study used tissue-based …