Brain cancer is regarded among the deadliest forms of cancer worldwide. The distinct tumor
microenvironment and inherent characteristics of brain tumor cells virtually render them …

Mn (III) ortho‐N‐alkyl‐and N‐alkoxyalkyl porphyrins (MnPs) were initially developed as
superoxide dismutase (SOD) mimics. These compounds were later shown to react with …

Liver damage upon exposure to ionizing radiation (IR), whether accidental or therapeutic,
can contribute to liver dysfunction. Currently, radiotherapy (RT) is used for various cancers …

Reactive oxygen species (ROS) are produced predominantly by the mitochondrial electron
transport chain and by NADPH oxidases in peroxisomes and in the endoplasmic reticulum …

The history of metalloporphyrins dates back more than 200 years ago. Metalloporphyrins are
excellent catalysts, capable of forming supramolecular systems, participate in oxygen …

Simple Summary Oxidative stress affects several features of cancer, including those related
to metastases formation. Non-small cell lung cancer (NSCLC) is commonly detected in …

Toxicities associated with radiation therapy are common, symptomatically devastating, and
costly. The best chance to effectively mitigate radiation-associated normal tissue side effects …

Gliomas are the most common type of primary brain tumors, presenting high mortality and
recurrence rates that highlight the need for the development of more efficient therapies. In …

Introduction Oxidative stress due to excess reactive oxygen species (ROS) is related to
many chronic illnesses including degenerative disc disease and osteoarthritis. MnTnBuOE-2 …

The manganese (III) porphyrin MnTnHex-2-PyP5+ (MnTnHex) is a potent superoxide
dismutase mimic and modulator of redox-based transcriptional activity that has been studied …