Cell types are the basic building blocks of multicellular organisms and are extensively
diversified in animals. Despite recent advances in characterizing cell types, classification …

The vertebrate spinal cord comprises multiple functionally distinct neuronal cell types
arranged in characteristic positions. During development, these different types of neurons …

Itch is a topic to which everyone can relate. The physiological roles of itch are increasingly
understood and appreciated. The pathophysiological consequences of itch impact quality of …

Aggressive neuroendocrine lung cancers, including small cell lung cancer (SCLC) and non-
small cell lung cancer (NSCLC), represent an understudied tumor subset that accounts for …

The spinal cord integrates and relays somatosensory input, leading to complex motor
responses. Research over the past couple of decades has identified transcription factor …

Pioneer transcription factors are thought to play pivotal roles in developmental processes by
binding nucleosomal DNA to activate gene expression, though mechanisms through which …

The proneural transcription factor Ascl1 coordinates gene expression in both proliferating
and differentiating progenitors along the neuronal lineage. Here, we used a cellular model …

The transcriptome of every cell is orchestrated by the complex network of interaction
between transcription factors (TFs) and their binding sites on DNA. Disruption of this network …

The development of the vertebrate spinal cord involves the formation of the neural tube and
the generation of multiple distinct cell types. The process starts during gastrulation …

The broad range of tissue and cellular diversity of animals is generated to a large extent by
the hierarchical deployment of sequence‐specific transcription factors and co‐factors …