Polycystic ovary syndrome: an evolutionary adaptation to lifestyle and the environment

J Parker, C O'brien, J Hawrelak, FL Gersh - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …

Network-based integrated analysis for toxic effects of high-concentration formaldehyde inhalation exposure through the toxicogenomic approach

DS Kang, N Lee, DY Shin, YJ Jang, SH Lee, KM Lim… - Scientific Reports, 2022 - nature.com
Formaldehyde is a colorless, pungent, highly reactive, and toxic environmental pollutant
used in various industries and products. Inhaled formaldehyde is a human and animal …

Probiotic reduced the impact of phthalates and bisphenol A mixture on type 2 diabetes mellitus development: Merging bioinformatics with in vivo analysis

K Baralić, K Živančević, D Jorgovanović… - food and chemical …, 2021 - Elsevier
Abstract Linkage between bis (2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP), and
bisphenol A (BPA) co-exposure and type 2 diabetes mellitus (T2DM), as well as ability of …

In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α …

H Bu, S Tang, G Liu, C Miao, X Zhou, H Yang, B Liu - Toxicology, 2023 - Elsevier
Dibutyl phthalate (DBP) is widely used in perfumes, cosmetics, shampoos and medical
devices. It is ubiquitous in the environment and greatly endangers people's health. Several …

Membrane polarization in non-neuronal cells as a potential mechanism of metabolic disruption by depolarizing insecticides

Y Park, A Suvorov, SB Symington, JM Clark - Food and Chemical …, 2022 - Elsevier
A significant rise in the incidence of obesity and type 2 diabetes has occurred worldwide in
the last two decades. Concurrently, a growing body of evidence suggests a connection …

[PDF][PDF] Potential genomic biomarkers of obesity and its comorbidities for phthalates and bisphenol A mixture: In silico toxicogenomic approach

K Baralić, K Živančević, D Božić, D Jennen… - Biocell, 2022 - cdn.techscience.cn
Potential genomic biomarkers of obesity and its comorbidities for phthalates and bisphenol A
mixture: In silico toxicogenomic ap Page 1 Potential genomic biomarkers of obesity and its …

Integrating in silico with in vivo approach to investigate phthalate and bisphenol A mixture-linked asthma development: Positive probiotic intervention

K Baralić, D Bozic, K Živančević, M Milenković… - Food and Chemical …, 2021 - Elsevier
The aim of this study was to explore the mechanisms of bis (2-ethylhexyl) phthalate (DEHP),
dibutyl phthalate (DBP) and bisphenol A (BPA) mixture-induced asthma development and …

Toxicogenomic analysis of physiologically important metals: An integrated in silico approach

S Balasubramanian, V Duraikannan… - Food and Chemical …, 2023 - Elsevier
Biologically important metals regulate cellular homeostasis in living systems. Anthropogenic
exposure to these metals can cause adverse effects, including an increased incidence of …

Developmental Exposures to Common Environmental Pollutants Result in Long-Term Reprogramming of Hypothalamic-Pituitary Axis in Mice

JP Mogus, M Marin, O Arowolo, V Salemme… - Environmental …, 2024 - Elsevier
Humans are exposed to a range of endocrine disrupting chemicals (EDCs). Many studies
demonstrate that exposures to EDCs during critical windows of development can …

Towards whole health toxicology: in-silico prediction of diseases sensitive to multi-chemical exposures

O Arowolo, V Salemme, A Suvorov - Toxics, 2022 - mdpi.com
Chemical exposures from diverse sources merge on a limited number of molecular
pathways described as toxicity pathways. Changes in the same set of molecular pathways in …