Biosensor-guided discovery and engineering of metabolic enzymes
A variety of chemicals have been produced through metabolic engineering approaches, and
enhancing biosynthesis performance can be achieved by using enzymes with high catalytic …
enhancing biosynthesis performance can be achieved by using enzymes with high catalytic …
Functionalized polysaccharides improve sensitivity of tyramide/peroxidase proximity labeling assays through electrostatic interactions
M Heiniger, R Vanella, Z Walsh-Korb… - … Biomaterials Science & …, 2024 - ACS Publications
High-throughput assays that efficiently link genotype and phenotype with high fidelity are
key to successful enzyme engineering campaigns. Among these assays, the …
key to successful enzyme engineering campaigns. Among these assays, the …
Rapid and Sensitive Biosensing of Salmonella Using Mechanical Step Rotation and Gold@platinum Nanozymatic Amplification
M Li, L Wang, A Xu, Y Ding, F Yang, Y Li… - Journal of Analysis and …, 2024 - Springer
Inspired by ballpoint pen, an optical biosensor is developed for detection of Salmonella
using a mechanical step rotator with a dropper to greatly simplify operation, a high gradient …
using a mechanical step rotator with a dropper to greatly simplify operation, a high gradient …
Amber Codon Mutational Scanning and Bioorthogonal PEGylation for Mapping Antibody Binding Sites on Human Arginase-1
Epitope mapping is crucial for understanding immunological responses to protein
therapeutics. Here, we combined genetic code expansion and bacterial surface display to …
therapeutics. Here, we combined genetic code expansion and bacterial surface display to …
Dissecting the Biophysical Origins of Activity-Stability Tradeoffs in D-Amino Acid Oxidase with Enzyme Proximity-Seq
Understanding the complex relationships between enzyme sequence, folding stability and
catalytic activity is crucial for applications in industry and biomedicine. However, current …
catalytic activity is crucial for applications in industry and biomedicine. However, current …
Understanding activity-stability tradeoffs in biocatalysts by enzyme proximity sequencing
Understanding the complex relationships between enzyme sequence, folding stability and
catalytic activity is crucial for applications in industry and biomedicine. However, current …
catalytic activity is crucial for applications in industry and biomedicine. However, current …