3-Amino-2-oxindoles bearing tetra-substituted stereocenter are very important constituents of many bioactive and pharmaceutical agents. In the last few years, asymmetric …
N Hara, S Nakamura, M Sano, R Tamura… - … A European Journal, 2012 - Wiley Online Library
The organocatalytic enantioselective decarboxylative addition of malonic acid half thioesters to ketimines derived from isatins by using N‐heteroarenesulfonyl cinchona alkaloid amides …
A quinine‐derived thiourea organocatalyst promoted the highly enantioselective addition of naphthols and activated phenols to ketimines derived from isatins. The reaction afforded …
F Zhou, FM Liao, JS Yu, J Zhou - Synthesis, 2014 - thieme-connect.com
The catalytic asymmetric electrophilic amination has been established as a fruitful methodology for the construction of nitrogen-bearing tetrasubstituted carbon stereocenters …
T Arai, E Matsumura, H Masu - Organic letters, 2014 - ACS Publications
An (S, S)-diphenyldiamine-derived bis (imidazolidine) pyridine (PyBidine)-NiCl2 complex catalyzed the nitro-Mannich reaction of isatin-derived N-Boc ketimines to construct a chiral …
K Ohmatsu, Y Ando, T Nakashima, T Ooi - Chem, 2016 - cell.com
Direct catalytic methods for the stereoselective introduction of various non-protected amines at the carbon atom adjacent to a carbonyl group remain elusive in synthetic chemistry, even …
Several oxindole derivatives, of natural or synthetic origin, have been identified as medicinally appealing compounds, with a plethora of bioactivities reported. Chiral 3-hydroxy …
D Chen, MH Xu - Chemical Communications, 2013 - pubs.rsc.org
Zn-mediated asymmetric allylation of N-tert -butanesulfinyl ketimines : an efficient and practical access to chiral quaternary 3-aminooxindoles - Chemical Communications (RSC …
S Hajra, S Singha Roy, A Biswas… - The Journal of Organic …, 2018 - ACS Publications
A simple catalyst-free method was developed for the ring opening of spiroaziridine oxindoles by three different nucleophiles, namely, amines, thiols, and methanol, to produce …