Recent advances in organocatalytic methods for the synthesis of disubstituted 2-and 3-indolinones

R Dalpozzo, G Bartoli, G Bencivenni - Chemical Society Reviews, 2012 - pubs.rsc.org
In recent years, organocatalysis has enhanced its importance as a tool for the synthesis of
enantiomerically enriched compounds. Among the candidates for organocatalysis, the …

Organocatalytic asymmetric synthesis of 3-amino-2-oxindole derivatives bearing a tetra-substituted stereocenter

P Chauhan, SS Chimni - Tetrahedron: Asymmetry, 2013 - Elsevier
3-Amino-2-oxindoles bearing tetra-substituted stereocenter are very important constituents
of many bioactive and pharmaceutical agents. In the last few years, asymmetric …

Enantioselective Synthesis of AG‐041R by using N‐Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts

N Hara, S Nakamura, M Sano, R Tamura… - … A European Journal, 2012 - Wiley Online Library
The organocatalytic enantioselective decarboxylative addition of malonic acid half thioesters
to ketimines derived from isatins by using N‐heteroarenesulfonyl cinchona alkaloid amides …

Organocatalytic Asymmetric Addition of Naphthols and Electron‐Rich Phenols to Isatin‐Derived Ketimines: Highly Enantioselective Construction of Tetrasubstituted …

M Montesinos‐Magraner, C Vila, R Cantón… - Angewandte …, 2015 - Wiley Online Library
A quinine‐derived thiourea organocatalyst promoted the highly enantioselective addition of
naphthols and activated phenols to ketimines derived from isatins. The reaction afforded …

Catalytic asymmetric electrophilic amination reactions to form nitrogen-bearing tetrasubstituted carbon stereocenters

F Zhou, FM Liao, JS Yu, J Zhou - Synthesis, 2014 - thieme-connect.com
The catalytic asymmetric electrophilic amination has been established as a fruitful
methodology for the construction of nitrogen-bearing tetrasubstituted carbon stereocenters …

Bis(imidazolidine)pyridine-NiCl2 Catalyst for Nitro-Mannich Reaction of Isatin-Derived N-Boc Ketimines: Asymmetric Synthesis of Chiral 3-Substituted 3-Amino-2 …

T Arai, E Matsumura, H Masu - Organic letters, 2014 - ACS Publications
An (S, S)-diphenyldiamine-derived bis (imidazolidine) pyridine (PyBidine)-NiCl2 complex
catalyzed the nitro-Mannich reaction of isatin-derived N-Boc ketimines to construct a chiral …

A modular strategy for the direct catalytic asymmetric α-amination of carbonyl compounds

K Ohmatsu, Y Ando, T Nakashima, T Ooi - Chem, 2016 - cell.com
Direct catalytic methods for the stereoselective introduction of various non-protected amines
at the carbon atom adjacent to a carbonyl group remain elusive in synthetic chemistry, even …

Recent advances in the asymmetric catalytic synthesis of chiral 3-hydroxy and 3-aminooxindoles and derivatives: Medicinally relevant compounds

P Brandao, AJ Burke - Tetrahedron, 2018 - Elsevier
Several oxindole derivatives, of natural or synthetic origin, have been identified as
medicinally appealing compounds, with a plethora of bioactivities reported. Chiral 3-hydroxy …

Zn-mediated asymmetric allylation of N-tert-butanesulfinyl ketimines: an efficient and practical access to chiral quaternary 3-aminooxindoles

D Chen, MH Xu - Chemical Communications, 2013 - pubs.rsc.org
Zn-mediated asymmetric allylation of N-tert -butanesulfinyl ketimines : an efficient and
practical access to chiral quaternary 3-aminooxindoles - Chemical Communications (RSC …

Catalyst-free ring opening of spiroaziridine oxindoles by heteronucleophiles: An approach to the synthesis of enantiopure 3-substituted oxindoles

S Hajra, S Singha Roy, A Biswas… - The Journal of Organic …, 2018 - ACS Publications
A simple catalyst-free method was developed for the ring opening of spiroaziridine
oxindoles by three different nucleophiles, namely, amines, thiols, and methanol, to produce …