From protein building blocks to functional materials

Y Shen, A Levin, A Kamada, Z Toprakcioglu… - ACS …, 2021 - ACS Publications
Proteins are the fundamental building blocks for high-performance materials in nature. Such
materials fulfill structural roles, as in the case of silk and collagen, and can generate active …

Stability matters, too–the thermodynamics of amyloid fibril formation

AK Buell - Chemical Science, 2022 - pubs.rsc.org
Amyloid fibrils are supramolecular homopolymers of proteins that play important roles in
biological functions and disease. These objects have received an exponential increase in …

Liquid nuclear condensates mechanically sense and restructure the genome

Y Shin, YC Chang, DSW Lee, J Berry, DW Sanders… - Cell, 2018 - cell.com
Phase transitions involving biomolecular liquids are a fundamental mechanism underlying
intracellular organization. In the cell nucleus, liquid-liquid phase separation of intrinsically …

Lysozyme amyloid fibril-integrated PEG injectable hydrogel adhesive with improved antiswelling and antibacterial capabilities

T Chen, Y Wang, J Xie, X Qu, C Liu - Biomacromolecules, 2022 - ACS Publications
Hydrogels with inherent antibacterial activities have been attracting increasing attention,
particularly for biomedical applications. Biology provides a range of materials and …

Recent advances in microgels: from biomolecules to functionality

Y Xu, H Zhu, A Denduluri, Y Ou, NA Erkamp, R Qi… - Small, 2022 - Wiley Online Library
The emerging applications of hydrogel materials at different length scales, in areas ranging
from sustainability to health, have driven the progress in the design and manufacturing of …

Self-assembled peptide nanostructures for functional materials

MS Ekiz, G Cinar, MA Khalily, MO Guler - Nanotechnology, 2016 - iopscience.iop.org
Nature is an important inspirational source for scientists, and presents complex and elegant
examples of adaptive and intelligent systems created by self-assembly. Significant effort has …

Aromatic short peptide architectonics: Assembly and engineering

K Tao, H Wu, L Adler-Abramovich, J Zhang… - Progress in Materials …, 2024 - Elsevier
Since the report of diphenylalanine (FF) peptide self-assembly into discrete nanostructures
in 2003, aromatic short peptide architectonics have been extensively studied globally and …

Liquid–Liquid Phase‐Separated Systems from Reversible Gel–Sol Transition of Protein Microgels

Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer… - Advanced …, 2021 - Wiley Online Library
Liquid–liquid phase‐separated biomolecular systems are increasingly recognized as key
components in the intracellular milieu where they provide spatial organization to the …

Microfluidics for protein biophysics

J Charmet, P Arosio, TPJ Knowles - Journal of molecular biology, 2018 - Elsevier
Microfluidics has the potential to transform experimental approaches across the life
sciences. In this review, we discuss recent advances enabled by the development and …

Deciphering the structure and formation of amyloids in neurodegenerative diseases with chemical biology tools

I Landrieu, E Dupré, D Sinnaeve, L El Hajjar… - Frontiers in …, 2022 - frontiersin.org
Protein aggregation into highly ordered, regularly repeated cross-β sheet structures called
amyloid fibrils is closely associated to human disorders such as neurodegenerative …