Type 2 diabetes mellitus in adults: Pathogenesis, prevention and therapy

X Lu, Q Xie, X Pan, R Zhang, X Zhang… - … and Targeted Therapy, 2024 - nature.com
Abstract Type 2 diabetes (T2D) is a disease characterized by heterogeneously progressive
loss of islet β cell insulin secretion usually occurring after the presence of insulin resistance …

Advances of traditional Chinese medicine preclinical mechanisms and clinical studies on diabetic peripheral neuropathy

Y Zhang, X Wu, W Yao, Y Ni, X Ding - Pharmaceutical Biology, 2024 - Taylor & Francis
Context Diabetic peripheral neuropathy (DPN) results in an enormous burden and reduces
the quality of life for patients. Considering there is no specific drug for the management of …

[HTML][HTML] Novel therapeutical approaches based on neurobiological and genetic strategies for diabetic polyneuropathy–A review

EK Sher, A Džidić-Krivić, A Karahmet… - Diabetes & Metabolic …, 2023 - Elsevier
Background Neuropathy is among the most often reported consequences of diabetes and
the biggest cause of morbidity and mortality in people suffering from this life-long disease …

High-intensity interval training, caloric restriction, or their combination have beneficial effects on metabolically acquired peripheral neuropathy

SA Eid, SE Elzinga, B Kim, AE Rumora, JM Hayes… - Diabetes, 2024 - diabetesjournals.org
Peripheral neuropathy (PN) is a prevalent and debilitating complication of obesity,
prediabetes, and type 2 diabetes, which remains poorly understood and lacks disease …

[HTML][HTML] An advanced chitosan based sponges dressing system with antioxidative, immunoregulation, angiogenesis and neurogenesis for promoting diabetic wound …

X Fan, Z Su, W Zhang, H Huang, C He, Z Wu… - Materials Today Bio, 2024 - Elsevier
Promoting wound nerve regeneration and synchronously initiating angiogenesis are critical
factors in the healing process of diabetic wounds. However, existing research on diabetic …

Metabolic memory: mechanisms and diseases

H Dong, Y Sun, L Nie, A Cui, P Zhao… - Signal transduction and …, 2024 - nature.com
Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …

[HTML][HTML] Dioscin: Therapeutic potential for diabetes and complications

H Gao, Z Wang, D Zhu, L Zhao, W Xiao - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Diabetes mellitus is a widespread metabolic disorder with increasing incidence worldwide,
posing a considerable threat to human health because of its complications. Therefore, cost …

The dynamics of nerve degeneration and regeneration in a healthy milieu and in diabetes

LB Dahlin - International Journal of Molecular Sciences, 2023 - mdpi.com
Appropriate animal models, mimicking conditions of both health and disease, are needed to
understand not only the biology and the physiology of neurons and other cells under normal …

Celecoxib ameliorates diabetic sarcopenia by inhibiting inflammation, stress response, mitochondrial dysfunction, and subsequent activation of the protein …

C Deng, C Lu, K Wang, M Chang, Y Shen… - Frontiers in …, 2024 - frontiersin.org
Aim: Diabetic sarcopenia leads to disability and seriously affects the quality of life. Currently,
there are no effective therapeutic strategies for diabetic sarcopenia. Our previous studies …

Assessing the diagnostic utility of urinary albumin-to-creatinine ratio as a potential biomarker for diabetic peripheral neuropathy in type 2 diabetes mellitus patients

H Zhang, S Yang, H Wang… - Scientific Reports, 2024 - nature.com
Background and aims Diabetic peripheral neuropathy (DPN) and diabetic nephropathy (DN)
both have microcirculation dysfunction. Urinary albumin-to-creatinine ratio (UACR) is a …