A High-Coverage Mesolithic Aurochs Genome and Effective Leveraging of Ancient Cattle Genomes Using Whole Genome Imputation

JAM Erven, A Scheu, MP Verdugo… - Molecular Biology …, 2024 - academic.oup.com
Ancient genomic analyses are often restricted to utilizing pseudohaploid data due to low
genome coverage. Leveraging low-coverage data by imputation to calculate phased diploid …

[HTML][HTML] Imputation strategies for low-coverage whole-genome sequencing data and their effects on genomic prediction and genome-wide association studies in pigs

XQ Wang, LG Wang, LY Shi, JJ Tian, MY Li, LX Wang… - animal, 2024 - Elsevier
The uncertainty resulting from missing genotypes in low-coverage whole-genome
sequencing (LCWGS) data complicates genotype imputation. The aim of this study is to find …

[HTML][HTML] Genomic Landscape and Prediction of Udder Traits in Saanen Dairy Goats

X Yao, J Li, J Fu, X Wang, L Ma, HA Nanaei, AM Shah… - Animals, 2025 - mdpi.com
Goats are essential to the dairy industry in Shaanxi, China, with udder traits playing a critical
role in determining milk production and economic value for breeding programs. However …

[HTML][HTML] Genomic Selection and WssGWAS of Sheep Body Weight and Milk Yield: Imputing Low-Coverage Sequencing Data with Similar Genetic Background Panels

D Li, Y Xiao, X Chen, Z Chen, X Zhao, X Xu, R Li… - Journal of Dairy …, 2025 - Elsevier
Low-coverage whole-genome sequencing (LcWGS), a cost-effective genotyping method,
offers greater flexibility in variant detection than does single-nucleotide polymorphism (SNP) …

[HTML][HTML] Local Ancestry and Adaptive Introgression in Xiangnan Cattle

H Yan, J Li, K Zhang, H Duan, A Sun, B Zhang, F Li… - Biology, 2024 - mdpi.com
Exploring the genetic landscape of native cattle is an exciting avenue for elucidating
nuanced patterns of genetic variation and adaptive dynamics. Xiangnan cattle, a native …

[HTML][HTML] Evaluating the Efficacy of Target Capture Sequencing for Genotyping in Cattle

Y Ren, MS Khatkar, C MacPhillamy, H Wang… - Genes, 2024 - mdpi.com
(1) Background: Target capture sequencing (TCS) is potentially a cost-effective way to detect
single-nucleotide polymorphisms (SNPs) and an alternative to SNP array-based …

A multi-tissue atlas of allelic-specific expression reveals the characteristics, mechanisms, and relationship with dominant effects in cattle

J Li, L Xu, X Liang, L Li, X Huang, Q Chen - 2025 - researchsquare.com
Background Allele-specific expression (ASE) analysis is a crucial tool for validating
expression quantitative trait loci (eQTLs), identifying causal variants associated with …

[HTML][HTML] Jiaqi Li 1 Lei Xu 1 Xiaoyun Liang 1 Letian Li 1 Xixia Huang 1✉ Email au-huangxixia@ 163. com

J Li, L Xu - assets-eu.researchsquare.com
Background Allele-specific expression (ASE) analysis is a crucial tool for validating
expression quantitative trait loci (eQTLs), identifying causal variants associated with …

INTEGRATED GLOBAL CHICKEN REFERENCE PANEL FROM 13,187 CHICKEN GENOMES

D Zhu, Y Wang, H Qu, C Feng, H Zhang, Z Sheng… - bioRxiv, 2023 - biorxiv.org
Chickens are a crucial source of protein for humans and a popular model animal for bird
research. Despite the emergence of imputation as a reliable genotyping strategy for large …