Major data analysis errors invalidate cancer microbiome findings

A Gihawi, Y Ge, J Lu, D Puiu, A Xu, CS Cooper… - MBio, 2023 - Am Soc Microbiol
We re-analyzed the data from a recent large-scale study that reported strong correlations
between DNA signatures of microbial organisms and 33 different cancer types and that …

Circulating extracellular vesicles carrying Firmicutes reflective of the local immune status may predict clinical response to pembrolizumab in urothelial carcinoma …

K Jingushi, A Kawashima, T Saito, T Kanazawa… - Cancer Immunology …, 2022 - Springer
Bacterial flora has clinical significance for the host. The metabolic environment created by
this flora influences immunotherapy in urothelial carcinoma. However, there are no reports …

Tumor and pan-tumor diversity and heterogeneity of cancer tissue microbiomes: a medical ecology analysis across 32 cancer types

Z Ma - medRxiv, 2024 - medrxiv.org
Diversity and heterogeneity are hallmarks of any ecosystems including cancer ecosystems.
Tumor heterogeneities have been a hot spot in cancer research because of their critical …