Background Benzodiazepine misuse is a growing public health problem, with increases in
benzodiazepine-related overdose deaths and emergency room visits in recent years …

Only a few recently published studies analyzed sex differences related to prescription opioid
use. Findings from the literature and our data suggest women are more likely to use …

In the midst of the current coronavirus pandemic, the United States continues to struggle with
an ongoing opioid epidemic, initially fueled by widespread prescribing of opioid medications …

An abundance of data indicates there are sex differences in endogenous opioid peptides
and opioid receptors, leading to functional differences in sensitivity to opioid receptor …

Background Opioid withdrawal is a key driver of opioid addiction and an obstacle to
recovery. However, withdrawal effects on opioid reinforcement and mesolimbic …

Objective There is a significant interindividual variability in treatment outcomes in
methadone maintenance treatment (MMT) for opioid use disorder (OUD). This prospective …

Abstract Background The Opioid Reduction Act (SB 273) took effect in West Virginia in June
2018. This legislation limited ongoing chronic opioid prescriptions to 30 days' supply, and …

Despite high rates of cannabis use during medication-based treatment of opioid use
disorder (MOUD), uncertainty remains around how cannabis influences treatment outcomes …

Background: Loneliness has been linked to greater substance use, especially among
women. Yet little is known about how loneliness is associated with treatment outcomes for …

As treatment expansion in the opioid epidemic continues, it is important to examine how the
makeup of individuals with opioid use disorder (OUD) is evolving. Treatment programs are …