Bronchial smooth muscle cell in asthma: where does it fit?

D Hassoun, L Rose, FX Blanc… - BMJ open …, 2022 - bmjopenrespres.bmj.com
Asthma is a frequent respiratory condition whose pathophysiology relies on altered
interactions between bronchial epithelium, smooth muscle cells (SMC) and immune …

Recent developments in bronchial thermoplasty for severe asthma

NC Thomson - Journal of asthma and allergy, 2019 - Taylor & Francis
Purpose Bronchial thermoplasty is approved in many countries worldwide as a non-
pharmacological treatment for severe asthma. This review summarizes recent publications …

Bronchial thermoplasty in asthma: an exploratory histopathological evaluation in distinct asthma endotypes/phenotypes

E Papakonstantinou, T Koletsa, L Zhou, L Fang… - Respiratory …, 2021 - Springer
Background Bronchial thermoplasty regulates structural abnormalities involved in airway
narrowing in asthma. In the present study we aimed to investigate the effect of bronchial …

[HTML][HTML] Bronchial thermoplasty attenuates bronchodilator responsiveness

C Henry, S Biardel, M Boucher, K Godbout, J Chakir… - Respiratory …, 2023 - Elsevier
Introduction Bronchial thermoplasty is an effective intervention to improve respiratory
symptoms and to reduce the rate of exacerbations in uncontrolled severe asthma. A …

Quantitative CT detects progression in COPD patients with severe emphysema in a 3-month interval

P Konietzke, MO Wielpütz, WL Wagner… - European …, 2020 - Springer
Objectives Chronic obstructive pulmonary disease (COPD) is characterized by variable
contributions of emphysema and airway disease on computed tomography (CT), and still …

Unmet needs in severe asthma subtyping and precision medicine trials. Bridging clinical and patient perspectives

S Siddiqui, LC Denlinger, SJ Fowler… - American journal of …, 2019 - atsjournals.org
Asthma affects 300 million people worldwide. Most patients with chronic asthma respond
well to currently available therapy. However, approximately 3–5% of patients have severe …

Qualitative and quantitative evaluation of computed tomography changes in adults with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor: a retrospective …

S Dettmer, O Weinheimer, A Sauer-Heilborn… - Frontiers in …, 2023 - frontiersin.org
Introduction: The availability of highly effective triple cystic fibrosis transmembrane
conductance regulator (CFTR) modulator combination therapy with elexacaftor–tezacaftor …

[HTML][HTML] Association of coronary artery calcification with clinical and physiological characteristics in patients with COPD: Results from COSYCONET

K Kahnert, RA Jörres, B Jobst, MO Wielpütz… - Respiratory …, 2022 - Elsevier
A bstract Chronic obstructive pulmonary disease (COPD) is frequently associated with
coronary artery disease (CAD). When considering computed tomography (CT) for COPD …

Low-Dose Whole-Chest Dynamic CT for the Assessment of Large Airway Collapsibility in Patients with Suspected Tracheobronchial Instability

A Bischoff, O Weinheimer, A Dutschke… - Radiology …, 2024 - pubs.rsna.org
Purpose To quantify tracheal collapsibility using low-dose four-dimensional (4D) CT and to
compare visual and quantitative 4D CT–based assessments with assessments from paired …

Echo Time‐Dependent Observed Lung T1 in Patients With Chronic Obstructive Pulmonary Disease in Correlation With Quantitative Imaging and Clinical Indices

SMF Triphan, O Weinheimer… - Journal of Magnetic …, 2021 - Wiley Online Library
Background There is a clinical need for imaging‐derived biomarkers for the management of
chronic obstructive pulmonary disease (COPD). Observed pulmonary T1 (T1 (TE)) depends …