From molecules to polymers—harnessing inter‐and intramolecular interactions to create mechanochromic materials

H Traeger, DJ Kiebala, C Weder… - Macromolecular rapid …, 2021 - Wiley Online Library
The development of mechanophores as building blocks that serve as predefined weak
linkages has enabled the creation of mechanoresponsive and mechanochromic polymer …

Environment-dependent single-chain mechanics of synthetic polymers and biomacromolecules by atomic force microscopy-based single-molecule force spectroscopy …

Y Bao, Z Luo, S Cui - Chemical Society Reviews, 2020 - pubs.rsc.org
“The Tao begets the One. One begets all things of the world.” This quote from Tao Te Ching
is still inspiring for scientists in chemistry and materials science: The “One” can refer to a …

Single-molecule spectroscopy of amino acids and peptides by recognition tunnelling

Y Zhao, B Ashcroft, P Zhang, H Liu, S Sen… - Nature …, 2014 - nature.com
The human proteome has millions of protein variants due to alternative RNA splicing and
post-translational modifications, and variants that are related to diseases are frequently …

Disease detection and management via single nanopore-based sensors

JE Reiner, A Balijepalli, JWF Robertson… - Chemical …, 2012 - ACS Publications
As nanometer-scale portals in biological membranes, protein ionic channels act as
gatekeepers, controlling the traffic of ions and macromolecules into and out of cells …

Correlating confocal microscopy and atomic force indentation reveals metastatic cancer cells stiffen during invasion into collagen I matrices

JR Staunton, BL Doss, S Lindsay, R Ros - Scientific reports, 2016 - nature.com
Mechanical interactions between cells and their microenvironment dictate cell phenotype
and behavior, calling for cell mechanics measurements in three-dimensional (3D) …

Resolving the molecular mechanism of cadherin catch bond formation

K Manibog, H Li, S Rakshit, S Sivasankar - Nature communications, 2014 - nature.com
Classical cadherin Ca2+-dependent cell–cell adhesion proteins play key roles in
embryogenesis and in maintaining tissue integrity. Cadherins mediate robust adhesion by …

Different roles of cadherins in the assembly and structural integrity of the desmosome complex

M Lowndes, S Rakshit, O Shafraz… - Journal of cell …, 2014 - journals.biologists.com
Adhesion between cells is established by the formation of specialized intercellular junctional
complexes, such as desmosomes. Desmosomes contain isoforms of two members of the …

Structure, energy, vibrational spectrum, and Bader's analysis of π⋯ H hydrogen bonds and H− δ⋯ H+ δ dihydrogen bonds

BG de Oliveira - Physical Chemistry Chemical Physics, 2013 - pubs.rsc.org
In this paper, the intermolecular structural study asserted by the vibrational analysis in the
stretch frequencies of hydrogen bonds (π⋯ H) and dihydrogen bonds (H− δ⋯ H+ δ) have …

Chemical recognition and binding kinetics in a functionalized tunnel junction

S Chang, S Huang, H Liu, P Zhang, F Liang… - …, 2012 - iopscience.iop.org
Abstract 4 (5)-(2-mercaptoethyl)-1H-imidazole-2-carboxamide is a molecule that has
multiple hydrogen bonding sites and a short flexible linker. When tethered to a pair of …

[HTML][HTML] Energy landscapes for base-flipping in a model DNA duplex

D Chakraborty, DJ Wales - The Journal of Physical chemistry. B, 2022 - ncbi.nlm.nih.gov
We explore the process of base-flipping for four central bases, adenine, guanine, cytosine,
and thymine, in a deoxyribonucleic acid (DNA) duplex using the energy landscape …