Hyaluronan–cisplatin conjugate nanoparticles embedded in Eudragit S100-coated pectin/alginate microbeads for colon drug delivery

SW Tsai, DS Yu, SW Tsao, FY Hsu - International Journal of …, 2013 - Taylor & Francis
Hyaluronan–cisplatin conjugate nanoparticles (HCNPs) were chosen as colon-targeting
drug-delivery carriers due to the observation that a variety of malignant tumors overexpress …

Optimization and formulation of fucoxanthin-loaded microsphere (F-LM) using response surface methodology (RSM) and analysis of its fucoxanthin release profile

I Jaswir, D Noviendri, M Taher, F Mohamed… - Molecules, 2019 - mdpi.com
Fucoxanthin has interesting anticancer activity, but is insoluble in water, hindering its use as
a drug. Microencapsulation is used as a technique for improving drug delivery. This study …

Exploiting microspheres as a therapeutic proficient doer for colon delivery: A review

A Vats, K Pathak - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Colon-specific drug delivery systems have recently gained importance for
delivering a variety of therapeutic agents via oral route. This mode offers the feasibility of …

Fabrication of fucoxanthin-loaded microsphere (F-LM) by two steps double-emulsion solvent evaporation method and characterization of fucoxanthin before and after …

D Noviendri, I Jaswir, M Taher, F Mohamed… - Journal of Oleo …, 2016 - jstage.jst.go.jp
Microencapsulation is a promising approach in drug delivery to protect the drug from
degradation and allow controlled release of the drug in the body. Fucoxanthin-loaded …

Formulation and optimization of celecoxib-loaded PLGA nanoparticles by the Taguchi design and their in vitro cytotoxicity for lung cancer therapy

J Emami, A Pourmashhadi, H Sadeghi… - Pharmaceutical …, 2015 - Taylor & Francis
The objective of the present study was to develop, evaluate and optimize a polymeric
nanoparticle (NP) system containing Cxb for pulmonary delivery of Cxb in the treatment of …

Development of pH-sensitive pectinate/alginate microspheres for colon drug delivery

FY Hsu, DS Yu, CC Huang - Journal of Materials Science: Materials in …, 2013 - Springer
The purposes of this study were to develop and evaluate calcium pectinate/alginate
microspheres (PAMs) and to exploit their pH-sensitive properties for colon-targeted delivery …

[HTML][HTML] Colon specific drug delivery of tramadol HCl for chronotherapeutics of arthritis

R Kadiyam, YI Muzib - International journal of pharmaceutical …, 2015 - ncbi.nlm.nih.gov
Objective: The objective of present work is to develop and evaluate a matrix system for
Chronotherapeutic delivery of centrally acting of opioid analgesic (tramadol HCl) to treat …

Cell Growth Inhibition Effect of DsiRNA Vectorised by Pectin‐Coated Chitosan‐Graphene Oxide Nanocomposites as Potential Therapy for Colon Cancer

H Katas, MCI Mohd Amin, N Moideen… - Journal of …, 2017 - Wiley Online Library
Colonic‐targeted drug delivery system is widely explored to combat colon‐related diseases
such as colon cancer. Dicer‐substrate small interfering RNA (DsiRNA) has been explored …

Efficient colonic delivery of DsiRNA by pectin-coated polyelectrolyte complex nanoparticles: preparation, characterization and improved gastric survivability

Z Hussain, H Katas, SL Yan… - Current Drug …, 2017 - ingentaconnect.com
Background: Despite having excellent anticancer efficacy and ability to knockdown gene
expression, the therapeutic feasibility of Dicer-substrate small interfering RNA (DsiRNA) is …

[PDF][PDF] Mucoadhesive microspheres for controlled delivery of drugs

M Khan, VA Ansari, P Kushwaha, A Kumar… - Asian J Pharm Clin …, 2015 - researchgate.net
Microspheres constitute an important part of the novel drug delivery system by virtue of their
small size and efficient carrying capacity. Due to their long residence time, bioadhesive …