Viruses of archaea represent one of the most enigmatic parts of the virosphere. Most of the
characterized archaeal viruses infect extremophilic hosts and display remarkable diversity of …

The Archaea—and their viruses—remain the most enigmatic of life's three domains. Once
thought to inhabit only extreme environments, archaea are now known to inhabit diverse …

Proteins belonging to PD-(D/E) XK phosphodiesterases constitute a functionally diverse
superfamily with representatives involved in replication, restriction, DNA repair and tRNA …

Geothermal and hypersaline environments are rich in virus-like particles, among which
spindle-shaped morphotypes dominate. Currently, viruses with spindle-or lemon-shaped …

The fungus Magnaporthe oryzae is a serious pathogen of rice and other grasses. Telomeric
restriction fragments in Magnaporthe isolates that infect perennial ryegrass (prg) are …

Sulfolobus turreted icosahedral virus (STIV) is a model archaeal virus and member of the
PRD1-adenovirus lineage. Although STIV employs pyramidal lysis structures to exit the host …

Csa3 family transcription factors are ancillary CRISPR-associated proteins composed of N-
terminal CARF domains and C-terminal winged helix-turn-helix domains. The activity of …

Cas10 is the signature gene for type III CRISPR–Cas surveillance complexes. Unlike type I
and type II systems, type III systems do not require a protospacer adjacent motif and target …

Fuselloviruses, also known as Sulfolobus Spindle-shaped viruses (SSVs), are “lemon”-or
“spindle”-shaped double-stranded DNA viruses. Among them, SSV1, SSV2 and the satellite …

Abstract PD-(D/E) XK nucleases, initially represented by only Type II restriction enzymes,
now comprise a large and extremely diverse superfamily of proteins. They participate in …