[HTML][HTML] Allorecognition and the spectrum of kidney transplant rejection

J Callemeyn, B Lamarthée, A Koenig, P Koshy… - Kidney International, 2022 - Elsevier
Detection of mismatched human leukocyte antigens by adaptive immune cells is considered
as the main cause of transplant rejection, leading to either T-cell mediated rejection or …

[HTML][HTML] The Banff 2022 Kidney Meeting Report: reappraisal of microvascular inflammation and the role of biopsy-based transcript diagnostics

M Naesens, C Roufosse, M Haas, C Lefaucheur… - American Journal of …, 2024 - Elsevier
Abstract The XVI-th Banff Meeting for Allograft Pathology was held at Banff, Alberta, Canada,
from 19th to 23rd September 2022, as a joint meeting with the Canadian Society of …

Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection

B Lamarthée, J Callemeyn, Y Van Herck… - Nature …, 2023 - nature.com
Rejection remains the main cause of premature graft loss after kidney transplantation,
despite the use of potent immunosuppression. This highlights the need to better understand …

[HTML][HTML] Diagnostic potential of minimally invasive biomarkers: a biopsy-centered viewpoint from the Banff Minimally Invasive Diagnostics Working Group

E Huang, M Mengel, MC Clahsen-van Groningen… - …, 2023 - journals.lww.com
With recent advances and commercial implementation of minimally invasive biomarkers in
kidney transplantation, new strategies for the surveillance of allograft health are emerging …

[HTML][HTML] The Banff 2022 Kidney Meeting Work Plan: data-driven refinement of the Banff Classification for renal allografts

C Roufosse, M Naesens, M Haas, C Lefaucheur… - American journal of …, 2024 - Elsevier
Abstract The XVIth Banff Meeting for Allograft Pathology was held in Banff, Alberta, Canada,
from September 19 to 23, 2022, as a joint meeting with the Canadian Society of …

[HTML][HTML] Automated urinary chemokine assays for noninvasive detection of kidney transplant rejection: a prospective cohort study

E Van Loon, C Tinel, H de Loor, X Bossuyt… - American Journal of …, 2024 - Elsevier
Rationale & Objective Prior studies have demonstrated the diagnostic potential of urinary
chemokines CXC motif ligand 9 (CXCL9) and CXCL10 for kidney transplant rejection …

Data-driven chronic allograft phenotypes: a novel and validated complement for histologic assessment of kidney transplant biopsies

T Vaulet, G Divard, O Thaunat, P Koshy… - Journal of the …, 2022 - journals.lww.com
Background No validated system currently exists to realistically characterize the chronic
pathology of kidney transplants that represents the dynamic disease process and spectrum …

Donor-specific antibody is associated with increased expression of rejection transcripts in renal transplant biopsies classified as no rejection

KS Madill-Thomsen, GA Böhmig… - Journal of the …, 2021 - journals.lww.com
Background Donor-specific HLA antibody (DSA) is present in many kidney transplant
patients whose biopsies are classified as no rejection (NR). We explored whether in some …

Machine learning‐supported interpretation of kidney graft elementary lesions in combination with clinical data

M Labriffe, JB Woillard, W Gwinner… - American Journal of …, 2022 - Wiley Online Library
Interpretation of kidney graft biopsies using the Banff classification is still heterogeneous. In
this study, extreme gradient boosting classifiers learned from two large training datasets (n …

Utility of Banff human organ transplant gene panel in human kidney transplant biopsies

RN Smith, IA Rosales, KT Tomaszewski… - …, 2023 - journals.lww.com
Background. Microarray transcript analysis of human renal transplantation biopsies has
successfully identified the many patterns of graft rejection. To evaluate an alternative, this …