Emerging roles and functional mechanisms of PIWI-interacting RNAs

X Wang, A Ramat, M Simonelig, MF Liu - Nature Reviews Molecular …, 2023 - nature.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …

[HTML][HTML] Principles and functions of pericentromeric satellite DNA clustering into chromocenters

F Brändle, B Frühbauer, M Jagannathan - Seminars in cell & …, 2022 - Elsevier
Simple non-coding tandem repeats known as satellite DNA are observed widely across
eukaryotes. These repeats occupy vast regions at the centromere and pericentromere of …

The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters

L Baumgartner, D Handler, SW Platzer, C Yu… - Elife, 2022 - elifesciences.org
RNA interference systems depend on the synthesis of small RNA precursors whose
sequences define the target spectrum of these silencing pathways. The Drosophila …

[HTML][HTML] New perspectives on the causes and consequences of male meiotic drive

C Courret, X Wei, AM Larracuente - Current Opinion in Genetics & …, 2023 - Elsevier
Gametogenesis is vulnerable to selfish genetic elements that bias their transmission to the
next generation by cheating meiosis. These so-called meiotic drivers are widespread in …

High levels of intra-strain structural variation in Drosophila simulans X pericentric heterochromatin

C Courret, AM Larracuente - Genetics, 2023 - academic.oup.com
Large genome structural variations can impact genome regulation and integrity. Repeat-rich
regions like pericentric heterochromatin are vulnerable to structural rearrangements …

Satellite DNAs in health and disease

Đ Ugarković, A Sermek, S Ljubić, I Feliciello - Genes, 2022 - mdpi.com
Tandemly repeated satellite DNAs are major components of centromeres and
pericentromeric heterochromatin which are crucial chromosomal elements responsible for …

Satellitome Analysis on Talpa aquitania Genome and Inferences about the satDNAs Evolution on Some Talpidae

J Gutiérrez, G Aleix-Mata, EE Montiel… - Genes, 2022 - mdpi.com
In the genus Talpa a new species, named Talpa aquitania, has been recently described.
Only cytogenetic data are available for the nuclear genome of this species. In this work, we …

Distinct spermiogenic phenotypes underlie sperm elimination in the Segregation Distorter meiotic drive system

M Herbette, X Wei, CH Chang, AM Larracuente… - PLoS …, 2021 - journals.plos.org
Segregation Distorter (SD) is a male meiotic drive system in Drosophila melanogaster.
Males heterozygous for a selfish SD chromosome rarely transmit the homologous SD+ …

Centromere-associated retroelement evolution in Drosophila melanogaster reveals an underlying conflict

LW Hemmer, S Negm, X Geng, C Courret… - BioRXiv, 2022 - biorxiv.org
Centromeres are chromosomal regions essential for coordinating chromosome segregation
during cell division. While centromeres are defined by the presence of a centromere-specific …

The implications of satellite DNA instability on cellular function and evolution

JM Flynn, YM Yamashita - Seminars in Cell & Developmental Biology, 2023 - Elsevier
Abundant tandemly repeated satellite DNA is present in most eukaryotic genomes. Previous
limitations including a pervasive view that it was uninteresting junk DNA, combined with …